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High Nuclease Activity of Long Persisting Staphylococcus aureus Isolates Within the Airways of Cystic Fibrosis Patients Protects Against NET-Mediated Killing.
Herzog S, Dach F, de Buhr N, Niemann S, Schlagowski J, Chaves-Moreno D, Neumann C, Goretzko J, Schwierzeck V, Mellmann A, Dübbers A, Küster P, Schültingkemper H, Rescher U, Pieper DH, von Köckritz-Blickwede M, Kahl BC. Herzog S, et al. Among authors: goretzko j. Front Immunol. 2019 Nov 5;10:2552. doi: 10.3389/fimmu.2019.02552. eCollection 2019. Front Immunol. 2019. PMID: 31772562 Free PMC article.
Targeting the endolysosomal host-SARS-CoV-2 interface by clinically licensed functional inhibitors of acid sphingomyelinase (FIASMA) including the antidepressant fluoxetine.
Schloer S, Brunotte L, Goretzko J, Mecate-Zambrano A, Korthals N, Gerke V, Ludwig S, Rescher U. Schloer S, et al. Among authors: goretzko j. Emerg Microbes Infect. 2020 Dec;9(1):2245-2255. doi: 10.1080/22221751.2020.1829082. Emerg Microbes Infect. 2020. PMID: 32975484 Free PMC article.
Repurposing Antifungals for Host-Directed Antiviral Therapy?
Schloer S, Goretzko J, Rescher U. Schloer S, et al. Among authors: goretzko j. Pharmaceuticals (Basel). 2022 Feb 10;15(2):212. doi: 10.3390/ph15020212. Pharmaceuticals (Basel). 2022. PMID: 35215323 Free PMC article. Review.
Disruption of the Rab7-Dependent Final Common Pathway of Endosomal and Autophagic Processing Results in a Severe Podocytopathy.
Vöing K, Michgehl U, Mertens ND, Picciotto C, Maywald ML, Goretzko J, Waimann S, Gilhaus K, Rogg M, Schell C, Klingauf J, Tsytsyura Y, Hansen U, van Marck V, Edinger AL, Vollenbröker B, Rescher U, Braun DA, George B, Weide T, Pavenstädt H. Vöing K, et al. Among authors: goretzko j. J Am Soc Nephrol. 2023 Jul 1;34(7):1191-1206. doi: 10.1681/ASN.0000000000000126. Epub 2023 Apr 5. J Am Soc Nephrol. 2023. PMID: 37022133
P-selectin-dependent leukocyte adhesion is governed by endolysosomal two-pore channel 2.
Goretzko J, Pauels I, Heitzig N, Thomas K, Kardell M, Naß J, Krogsaeter EK, Schloer S, Spix B, Linard Matos AL, Leser C, Wegner T, Glorius F, Bracher F, Gerke V, Rossaint J, Grimm C, Rescher U. Goretzko J, et al. Cell Rep. 2023 Dec 26;42(12):113501. doi: 10.1016/j.celrep.2023.113501. Epub 2023 Nov 30. Cell Rep. 2023. PMID: 38039128 Free article.