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Direct Evidence for Microdomain-Specific Localization and Remodeling of Functional L-Type Calcium Channels in Rat and Human Atrial Myocytes.
Glukhov AV, Balycheva M, Sanchez-Alonso JL, Ilkan Z, Alvarez-Laviada A, Bhogal N, Diakonov I, Schobesberger S, Sikkel MB, Bhargava A, Faggian G, Punjabi PP, Houser SR, Gorelik J. Glukhov AV, et al. Among authors: gorelik j. Circulation. 2015 Dec 22;132(25):2372-84. doi: 10.1161/CIRCULATIONAHA.115.018131. Epub 2015 Oct 8. Circulation. 2015. PMID: 26450916 Free PMC article.
The protective effect of ursodeoxycholic acid in an in vitro model of the human fetal heart occurs via targeting cardiac fibroblasts.
Schultz F, Hasan A, Alvarez-Laviada A, Miragoli M, Bhogal N, Wells S, Poulet C, Chambers J, Williamson C, Gorelik J. Schultz F, et al. Among authors: gorelik j. Prog Biophys Mol Biol. 2016 Jan;120(1-3):149-63. doi: 10.1016/j.pbiomolbio.2016.01.003. Epub 2016 Jan 8. Prog Biophys Mol Biol. 2016. PMID: 26777584 Free article.
Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure.
Sanchez-Alonso JL, Bhargava A, O'Hara T, Glukhov AV, Schobesberger S, Bhogal N, Sikkel MB, Mansfield C, Korchev YE, Lyon AR, Punjabi PP, Nikolaev VO, Trayanova NA, Gorelik J. Sanchez-Alonso JL, et al. Among authors: gorelik j. Circ Res. 2016 Sep 30;119(8):944-55. doi: 10.1161/CIRCRESAHA.116.308698. Epub 2016 Aug 29. Circ Res. 2016. PMID: 27572487 Free PMC article.
Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in β2AR-cAMP Responsiveness in Murine Hearts.
Wright PT, Bhogal NK, Diakonov I, Pannell LMK, Perera RK, Bork NI, Schobesberger S, Lucarelli C, Faggian G, Alvarez-Laviada A, Zaccolo M, Kamp TJ, Balijepalli RC, Lyon AR, Harding SE, Nikolaev VO, Gorelik J. Wright PT, et al. Among authors: gorelik j. Cell Rep. 2018 Apr 10;23(2):459-469. doi: 10.1016/j.celrep.2018.03.053. Cell Rep. 2018. PMID: 29642004 Free PMC article.
Studying signal compartmentation in adult cardiomyocytes.
Judina A, Gorelik J, Wright PT. Judina A, et al. Among authors: gorelik j. Biochem Soc Trans. 2020 Feb 28;48(1):61-70. doi: 10.1042/BST20190247. Biochem Soc Trans. 2020. PMID: 32104883 Free PMC article. Review.
130 results