Gopalakrishnan M - Search Results

1

Analysis Approaches to Identify Pharmacogenetic Associations With Pharmacodynamics.

Hertz DL, Ramsey LB, Gopalakrishnan M, Leeder JS, Van Driest SL. Hertz DL, et al. Among authors: gopalakrishnan m. Clin Pharmacol Ther. 2021 Sep;110(3):589-594. doi: 10.1002/cpt.2312. Epub 2021 Jun 28. Clin Pharmacol Ther. 2021. PMID: 34043820 Free PMC article. Review.

2

Model-Based Approach to Improve Clinical Outcomes in Neonates With Opioid Withdrawal Syndrome Using Real-World Data.

Wijekoon N, Aduroja O, Biggs JM, El-Metwally D, Gopalakrishnan M. Wijekoon N, et al. Among authors: gopalakrishnan m. Clin Pharmacol Ther. 2021 Jan;109(1):243-252. doi: 10.1002/cpt.2093. Epub 2020 Dec 16. Clin Pharmacol Ther. 2021. PMID: 33119888

3

Evaluation of Switch-to-Brand Rates as a Potential Signal for Therapeutic Equivalency of Generic Antidepressants: A Real-World Retrospective Cohort Study.

Kalaria S, Spence O, Hong K, dosReis S, Gopalakrishnan M. Kalaria S, et al. Among authors: gopalakrishnan m. Clin Pharmacol Ther. 2021 Aug;110(2):443-451. doi: 10.1002/cpt.2249. Epub 2021 Apr 27. Clin Pharmacol Ther. 2021. PMID: 33811324

4

Population Pharmacokinetics of an Intranasally Administered Combination of Oxymetazoline and Tetracaine in Healthy Volunteers.

Cacek AT, Gobburu JV, Gopalakrishnan M. Cacek AT, et al. Among authors: gopalakrishnan m. J Clin Pharmacol. 2017 Feb;57(2):247-254. doi: 10.1002/jcph.799. Epub 2016 Aug 23. J Clin Pharmacol. 2017. PMID: 27436060

5

Parent-Metabolite Pharmacokinetic Modeling and Pharmacodynamics of Veliparib (ABT-888), a PARP Inhibitor, in Patients With BRCA 1/2-Mutated Cancer or PARP-Sensitive Tumor Types.

Niu J, Scheuerell C, Mehrotra S, Karan S, Puhalla S, Kiesel BF, Ji J, Chu E, Gopalakrishnan M, Ivaturi V, Gobburu J, Beumer JH. Niu J, et al. Among authors: gopalakrishnan m. J Clin Pharmacol. 2017 Aug;57(8):977-987. doi: 10.1002/jcph.892. Epub 2017 Apr 7. J Clin Pharmacol. 2017. PMID: 28387939 Free PMC article. Clinical Trial.

6

A Quantitative Justification of Similarity in Placebo Response Between Adults and Adolescents With Acute Exacerbation of Schizophrenia in Clinical Trials.

Kalaria SN, Zhu H, Farchione TR, Mathis MV, Gopalakrishnan M, Uppoor R, Mehta M, Younis I. Kalaria SN, et al. Among authors: gopalakrishnan m. Clin Pharmacol Ther. 2019 Nov;106(5):1046-1055. doi: 10.1002/cpt.1501. Epub 2019 Jul 3. Clin Pharmacol Ther. 2019. PMID: 31069784

7

Assessment of Similarity in Antipsychotic Exposure-Response Relationships in Clinical Trials Between Adults and Adolescents With Acute Exacerbation of Schizophrenia.

Kalaria SN, Farchione TR, Mathis MV, Gopalakrishnan M, Younis I, Uppoor R, Mehta M, Wang Y, Zhu H. Kalaria SN, et al. Among authors: gopalakrishnan m. J Clin Pharmacol. 2020 Jul;60(7):848-859. doi: 10.1002/jcph.1580. Epub 2020 Jan 28. J Clin Pharmacol. 2020. PMID: 31994186

8

A prospective, real-world, clinical pharmacokinetic study to inform lacosamide dosing in critically ill patients undergoing continuous venovenous haemofiltration (PADRE-02).

Kalaria SN, Armahizer M, McCarthy P, Badjatia N, Gobburu JV, Gopalakrishnan M. Kalaria SN, et al. Among authors: gopalakrishnan m. Br J Clin Pharmacol. 2021 Nov;87(11):4375-4385. doi: 10.1111/bcp.14858. Epub 2021 May 5. Br J Clin Pharmacol. 2021. PMID: 33855736 Free article.

9

Reassessing the Pediatric Dosing Recommendations for Unfractionated Heparin Using Real-World Data: A Pharmacokinetic-Pharmacodynamic Modeling Approach.

Salem AM, Niu T, Li C, Moffett BS, Ivaturi V, Gopalakrishnan M. Salem AM, et al. Among authors: gopalakrishnan m. J Clin Pharmacol. 2022 Jun;62(6):733-746. doi: 10.1002/jcph.2007. Epub 2022 Jan 12. J Clin Pharmacol. 2022. PMID: 34816442

10

Pharmacokinetic Modeling Using Real-World Data to Optimize Unfractionated Heparin Dosing in Pediatric Patients on Extracorporeal Membrane Oxygenation and Evaluate Target Achievement-Clinical Outcomes Relationship.

Salem AM, Smith T, Wilkes J, Bailly DK, Heyrend C, Profsky M, Yellepeddi VK, Gopalakrishnan M. Salem AM, et al. Among authors: gopalakrishnan m. J Clin Pharmacol. 2024 Jan;64(1):30-44. doi: 10.1002/jcph.2333. Epub 2023 Sep 1. J Clin Pharmacol. 2024. PMID: 37565528

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