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Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cells.
Mariappan A, Soni K, Schorpp K, Zhao F, Minakar A, Zheng X, Mandad S, Macheleidt I, Ramani A, Kubelka T, Dawidowski M, Golfmann K, Wason A, Yang C, Simons J, Schmalz HG, Hyman AA, Aneja R, Ullrich R, Urlaub H, Odenthal M, Büttner R, Li H, Sattler M, Hadian K, Gopalakrishnan J. Mariappan A, et al. Among authors: gopalakrishnan j. EMBO J. 2019 Jan 15;38(2):e99876. doi: 10.15252/embj.201899876. Epub 2018 Dec 10. EMBO J. 2019. PMID: 30530478 Free PMC article.
Losers of Primary Cilia Gain the Benefit of Survival.
Goranci-Buzhala G, Gabriel E, Mariappan A, Gopalakrishnan J. Goranci-Buzhala G, et al. Among authors: gopalakrishnan j. Cancer Discov. 2017 Dec;7(12):1374-1375. doi: 10.1158/2159-8290.CD-17-1085. Cancer Discov. 2017. PMID: 29208776
Conserved TCP domain of Sas-4/CPAP is essential for pericentriolar material tethering during centrosome biogenesis.
Zheng X, Gooi LM, Wason A, Gabriel E, Mehrjardi NZ, Yang Q, Zhang X, Debec A, Basiri ML, Avidor-Reiss T, Pozniakovsky A, Poser I, Saric T, Hyman AA, Li H, Gopalakrishnan J. Zheng X, et al. Among authors: gopalakrishnan j. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):E354-63. doi: 10.1073/pnas.1317535111. Epub 2014 Jan 2. Proc Natl Acad Sci U S A. 2014. PMID: 24385583 Free PMC article.
CPAP promotes timely cilium disassembly to maintain neural progenitor pool.
Gabriel E, Wason A, Ramani A, Gooi LM, Keller P, Pozniakovsky A, Poser I, Noack F, Telugu NS, Calegari F, Šarić T, Hescheler J, Hyman AA, Gottardo M, Callaini G, Alkuraya FS, Gopalakrishnan J. Gabriel E, et al. Among authors: gopalakrishnan j. EMBO J. 2016 Apr 15;35(8):803-19. doi: 10.15252/embj.201593679. Epub 2016 Feb 29. EMBO J. 2016. PMID: 26929011 Free PMC article.
103 results