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Cerebrospinal fluid concentration of complement component 4A is increased in first episode schizophrenia.
Nat Commun. 2022 Nov 3;13(1):6427. doi: 10.1038/s41467-022-33797-6.
Nat Commun. 2022.
PMID: 36329007
Free PMC article.
Identification of Brain-Penetrant ATP-Competitive mTOR Inhibitors for CNS Syndromes.
Bonazzi S, Gray A, Thomsen NM, Biag J, Labbe-Giguere N, Keaney EP, Malik HA, Sun Y, Nunez J, Karki RG, Knapp M, Elling R, Fuller J, Pardee G, Craig L, Capre K, Salas S, Gorde A, Liang G, Lubicka D, McTighe SM, Goold C, Liu S, Deng L, Hong J, Fekete A, Stadelmann P, Frieauff W, Elhajouji A, Bauer D, Lerchner A, Radetich B, Furet P, Piizzi G, Burdette D, Wilson CJ, Peukert S, Hamann LG, Murphy LO, Curtis D.
Bonazzi S, et al.
J Med Chem. 2023 Jul 13;66(13):9095-9119. doi: 10.1021/acs.jmedchem.3c00705. Epub 2023 Jul 3.
J Med Chem. 2023.
PMID: 37399505
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Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders.
Bonazzi S, Goold CP, Gray A, Thomsen NM, Nunez J, Karki RG, Gorde A, Biag JD, Malik HA, Sun Y, Liang G, Lubicka D, Salas S, Labbe-Giguere N, Keaney EP, McTighe S, Liu S, Deng L, Piizzi G, Lombardo F, Burdette D, Dodart JC, Wilson CJ, Peukert S, Curtis D, Hamann LG, Murphy LO.
Bonazzi S, et al. Among authors: goold cp.
J Med Chem. 2020 Feb 13;63(3):1068-1083. doi: 10.1021/acs.jmedchem.9b01398. Epub 2020 Jan 31.
J Med Chem. 2020.
PMID: 31955578
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Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning.
Sellgren CM, Gracias J, Watmuff B, Biag JD, Thanos JM, Whittredge PB, Fu T, Worringer K, Brown HE, Wang J, Kaykas A, Karmacharya R, Goold CP, Sheridan SD, Perlis RH.
Sellgren CM, et al. Among authors: goold cp.
Nat Neurosci. 2019 Mar;22(3):374-385. doi: 10.1038/s41593-018-0334-7. Epub 2019 Feb 4.
Nat Neurosci. 2019.
PMID: 30718903
Free PMC article.
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Single-cell optogenetic excitation drives homeostatic synaptic depression.
Goold CP, Nicoll RA.
Goold CP, et al.
Neuron. 2010 Nov 4;68(3):512-28. doi: 10.1016/j.neuron.2010.09.020.
Neuron. 2010.
PMID: 21040851
Free PMC article.
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The BMP ligand Gbb gates the expression of synaptic homeostasis independent of synaptic growth control.
Goold CP, Davis GW.
Goold CP, et al.
Neuron. 2007 Oct 4;56(1):109-23. doi: 10.1016/j.neuron.2007.08.006.
Neuron. 2007.
PMID: 17920019
Free PMC article.
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Mechanisms underlying the rapid induction and sustained expression of synaptic homeostasis.
Frank CA, Kennedy MJ, Goold CP, Marek KW, Davis GW.
Frank CA, et al. Among authors: goold cp.
Neuron. 2006 Nov 22;52(4):663-77. doi: 10.1016/j.neuron.2006.09.029.
Neuron. 2006.
PMID: 17114050
Free PMC article.
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Regions in rat and human parathyroid hormone (PTH) 2 receptors controlling receptor interaction with PTH and with antagonist ligands.
Goold CP, Usdin TB, Hoare SR.
Goold CP, et al.
J Pharmacol Exp Ther. 2001 Nov;299(2):678-90.
J Pharmacol Exp Ther. 2001.
PMID: 11602681
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