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MicroRNA-126 induces autophagy by altering cell metabolism in malignant mesothelioma.
Tomasetti M, Monaco F, Manzella N, Rohlena J, Rohlenova K, Staffolani S, Gaetani S, Ciarapica V, Amati M, Bracci M, Valentino M, Goodwin J, Nguyen M, Truksa J, Sobol M, Hozak P, Dong LF, Santarelli L, Neuzil J. Tomasetti M, et al. Among authors: goodwin j. Oncotarget. 2016 Jun 14;7(24):36338-36352. doi: 10.18632/oncotarget.8916. Oncotarget. 2016. PMID: 27119351 Free PMC article.
MicroRNA-126 suppresses mesothelioma malignancy by targeting IRS1 and interfering with the mitochondrial function.
Tomasetti M, Nocchi L, Staffolani S, Manzella N, Amati M, Goodwin J, Kluckova K, Nguyen M, Strafella E, Bajzikova M, Peterka M, Lettlova S, Truksa J, Lee W, Dong LF, Santarelli L, Neuzil J. Tomasetti M, et al. Among authors: goodwin j. Antioxid Redox Signal. 2014 Nov 20;21(15):2109-25. doi: 10.1089/ars.2013.5215. Epub 2014 Apr 23. Antioxid Redox Signal. 2014. PMID: 24444362 Free PMC article.
Alpha-tocopheryl succinate inhibits autophagic survival of prostate cancer cells induced by vitamin K3 and ascorbate to trigger cell death.
Tomasetti M, Nocchi L, Neuzil J, Goodwin J, Nguyen M, Dong L, Manzella N, Staffolani S, Milanese C, Garrone B, Alleva R, Borghi B, Santarelli L, Guerrieri R. Tomasetti M, et al. Among authors: goodwin j. PLoS One. 2012;7(12):e52263. doi: 10.1371/journal.pone.0052263. Epub 2012 Dec 18. PLoS One. 2012. PMID: 23272231 Free PMC article.
Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents.
Pasdar EA, Smits M, Stapelberg M, Bajzikova M, Stantic M, Goodwin J, Yan B, Stursa J, Kovarova J, Sachaphibulkij K, Bezawork-Geleta A, Sobol M, Filimonenko A, Tomasetti M, Zobalova R, Hozak P, Dong LF, Neuzil J. Pasdar EA, et al. Among authors: goodwin j. PLoS One. 2015 May 1;10(5):e0119549. doi: 10.1371/journal.pone.0119549. eCollection 2015. PLoS One. 2015. PMID: 25932953 Free PMC article.
Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer.
Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork-Geleta A, Blecha J, Endaya B, Werner L, Cerny J, Zobalova R, Goodwin J, Spacek T, Alizadeh Pesdar E, Yan B, Nguyen MN, Vondrusova M, Sobol M, Jezek P, Hozak P, Truksa J, Rohlena J, Dong LF, Neuzil J. Rohlenova K, et al. Among authors: goodwin j. Antioxid Redox Signal. 2017 Jan 10;26(2):84-103. doi: 10.1089/ars.2016.6677. Epub 2016 Aug 22. Antioxid Redox Signal. 2017. PMID: 27392540 Free PMC article.
Indoleamine-2,3-dioxygenase elevated in tumor-initiating cells is suppressed by mitocans.
Stapelberg M, Zobalova R, Nguyen MN, Walker T, Stantic M, Goodwin J, Pasdar EA, Thai T, Prokopova K, Yan B, Hall S, de Pennington N, Thomas SR, Grant G, Stursa J, Bajzikova M, Meedeniya AC, Truksa J, Ralph SJ, Ansorge O, Dong LF, Neuzil J. Stapelberg M, et al. Among authors: goodwin j. Free Radic Biol Med. 2014 Feb;67:41-50. doi: 10.1016/j.freeradbiomed.2013.10.003. Epub 2013 Oct 18. Free Radic Biol Med. 2014. PMID: 24145120
Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA.
Tan AS, Baty JW, Dong LF, Bezawork-Geleta A, Endaya B, Goodwin J, Bajzikova M, Kovarova J, Peterka M, Yan B, Pesdar EA, Sobol M, Filimonenko A, Stuart S, Vondrusova M, Kluckova K, Sachaphibulkij K, Rohlena J, Hozak P, Truksa J, Eccles D, Haupt LM, Griffiths LR, Neuzil J, Berridge MV. Tan AS, et al. Among authors: goodwin j. Cell Metab. 2015 Jan 6;21(1):81-94. doi: 10.1016/j.cmet.2014.12.003. Cell Metab. 2015. PMID: 25565207 Free article.
Mitochondrially targeted vitamin E succinate modulates expression of mitochondrial DNA transcripts and mitochondrial biogenesis.
Truksa J, Dong LF, Rohlena J, Stursa J, Vondrusova M, Goodwin J, Nguyen M, Kluckova K, Rychtarcikova Z, Lettlova S, Spacilova J, Stapelberg M, Zoratti M, Neuzil J. Truksa J, et al. Among authors: goodwin j. Antioxid Redox Signal. 2015 Apr 10;22(11):883-900. doi: 10.1089/ars.2013.5594. Epub 2015 Feb 25. Antioxid Redox Signal. 2015. PMID: 25578105
Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapy.
Dong LF, Jameson VJ, Tilly D, Prochazka L, Rohlena J, Valis K, Truksa J, Zobalova R, Mahdavian E, Kluckova K, Stantic M, Stursa J, Freeman R, Witting PK, Norberg E, Goodwin J, Salvatore BA, Novotna J, Turanek J, Ledvina M, Hozak P, Zhivotovsky B, Coster MJ, Ralph SJ, Smith RA, Neuzil J. Dong LF, et al. Among authors: goodwin j. Free Radic Biol Med. 2011 Jun 1;50(11):1546-55. doi: 10.1016/j.freeradbiomed.2011.02.032. Epub 2011 Mar 12. Free Radic Biol Med. 2011. PMID: 21402148
Mitochondrially targeted α-tocopheryl succinate is antiangiogenic: potential benefit against tumor angiogenesis but caution against wound healing.
Rohlena J, Dong LF, Kluckova K, Zobalova R, Goodwin J, Tilly D, Stursa J, Pecinova A, Philimonenko A, Hozak P, Banerjee J, Ledvina M, Sen CK, Houstek J, Coster MJ, Neuzil J. Rohlena J, et al. Among authors: goodwin j. Antioxid Redox Signal. 2011 Dec 15;15(12):2923-35. doi: 10.1089/ars.2011.4192. Antioxid Redox Signal. 2011. PMID: 21902599 Free PMC article.
1,757 results