Goodwin BJ - Search Results

1

Identification of small molecule agonists of the orphan nuclear receptors liver receptor homolog-1 and steroidogenic factor-1.

Whitby RJ, Dixon S, Maloney PR, Delerive P, Goodwin BJ, Parks DJ, Willson TM. Whitby RJ, et al. Among authors: goodwin bj. J Med Chem. 2006 Nov 16;49(23):6652-5. doi: 10.1021/jm060990k. J Med Chem. 2006. PMID: 17154495

2

Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity.

Chao EY, Caravella JA, Watson MA, Campobasso N, Ghisletti S, Billin AN, Galardi C, Wang P, Laffitte BA, Iannone MA, Goodwin BJ, Nichols JA, Parks DJ, Stewart E, Wiethe RW, Williams SP, Smallwood A, Pearce KH, Glass CK, Willson TM, Zuercher WJ, Collins JL. Chao EY, et al. Among authors: goodwin bj. J Med Chem. 2008 Sep 25;51(18):5758-65. doi: 10.1021/jm800612u. J Med Chem. 2008. PMID: 18800767

3

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor.

Kast HR, Goodwin B, Tarr PT, Jones SA, Anisfeld AM, Stoltz CM, Tontonoz P, Kliewer S, Willson TM, Edwards PA. Kast HR, et al. J Biol Chem. 2002 Jan 25;277(4):2908-15. doi: 10.1074/jbc.M109326200. Epub 2001 Nov 12. J Biol Chem. 2002. PMID: 11706036 Free article.

4

Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes.

Maglich JM, Parks DJ, Moore LB, Collins JL, Goodwin B, Billin AN, Stoltz CA, Kliewer SA, Lambert MH, Willson TM, Moore JT. Maglich JM, et al. J Biol Chem. 2003 May 9;278(19):17277-83. doi: 10.1074/jbc.M300138200. Epub 2003 Feb 27. J Biol Chem. 2003. PMID: 12611900 Free article.

5

Identification of liver receptor homolog-1 as a novel regulator of apolipoprotein AI gene transcription.

Delerive P, Galardi CM, Bisi JE, Nicodeme E, Goodwin B. Delerive P, et al. Mol Endocrinol. 2004 Oct;18(10):2378-87. doi: 10.1210/me.2004-0132. Epub 2004 Jun 24. Mol Endocrinol. 2004. PMID: 15218078

6

Liver receptor homolog 1 is a negative regulator of the hepatic acute-phase response.

Venteclef N, Smith JC, Goodwin B, Delerive P. Venteclef N, et al. Mol Cell Biol. 2006 Sep;26(18):6799-807. doi: 10.1128/MCB.00579-06. Mol Cell Biol. 2006. PMID: 16943422 Free PMC article.

7

Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.

Moore LB, Parks DJ, Jones SA, Bledsoe RK, Consler TG, Stimmel JB, Goodwin B, Liddle C, Blanchard SG, Willson TM, Collins JL, Kliewer SA. Moore LB, et al. J Biol Chem. 2000 May 19;275(20):15122-7. doi: 10.1074/jbc.M001215200. J Biol Chem. 2000. PMID: 10748001 Free article.

8

The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism.

Kliewer SA, Goodwin B, Willson TM. Kliewer SA, et al. Endocr Rev. 2002 Oct;23(5):687-702. doi: 10.1210/er.2001-0038. Endocr Rev. 2002. PMID: 12372848 Review.

9

Nuclear receptor regulation of genes involved in bile acid metabolism.

Moore JT, Goodwin B, Willson TM, Kliewer SA. Moore JT, et al. Crit Rev Eukaryot Gene Expr. 2002;12(2):119-35. doi: 10.1615/critreveukaryotgeneexpr.v12.i2.30. Crit Rev Eukaryot Gene Expr. 2002. PMID: 12434926 Review.

10

The nuclear receptor CAR is a regulator of thyroid hormone metabolism during caloric restriction.

Maglich JM, Watson J, McMillen PJ, Goodwin B, Willson TM, Moore JT. Maglich JM, et al. J Biol Chem. 2004 May 7;279(19):19832-8. doi: 10.1074/jbc.M313601200. Epub 2004 Mar 5. J Biol Chem. 2004. PMID: 15004031 Free article.

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