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Structure-based optimisation of orally active & reversible MetAP-2 inhibitors maintaining a tight 'molecular budget'.
Hirst DJ, Brandt M, Bruton G, Christodoulou E, Cutler L, Deeks N, Goodacre JD, Jack T, Lindon M, Miah A, Page K, Parr N, Shukla L, Sims M, Thomas P, Thorpe J, Holmes DS. Hirst DJ, et al. Among authors: goodacre jd. Bioorg Med Chem Lett. 2020 Nov 1;30(21):127533. doi: 10.1016/j.bmcl.2020.127533. Epub 2020 Sep 10. Bioorg Med Chem Lett. 2020. PMID: 32919012
Rhodium-catalysed linear-selective alkyne hydroacylation.
Poingdestre SJ, Goodacre JD, Weller AS, Willis MC. Poingdestre SJ, et al. Among authors: goodacre jd. Chem Commun (Camb). 2012 May 22. doi: 10.1039/c2cc32713a. Online ahead of print. Chem Commun (Camb). 2012. PMID: 22618331
Novel conserved group A streptococcal proteins identified by the antigenome technology as vaccine candidates for a non-M protein-based vaccine.
Fritzer A, Senn BM, Minh DB, Hanner M, Gelbmann D, Noiges B, Henics T, Schulze K, Guzman CA, Goodacre J, von Gabain A, Nagy E, Meinke AL. Fritzer A, et al. Among authors: goodacre j. Infect Immun. 2010 Sep;78(9):4051-67. doi: 10.1128/IAI.00295-10. Epub 2010 Jul 12. Infect Immun. 2010. PMID: 20624906 Free PMC article.
58 results