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Page 1
Cannabinoid derivatives exert a potent anti-myeloma activity both in vitro and in vivo.
Barbado MV, Medrano M, Caballero-Velázquez T, Álvarez-Laderas I, Sánchez-Abarca LI, García-Guerrero E, Martín-Sánchez J, Rosado IV, Piruat JI, Gonzalez-Naranjo P, Campillo NE, Páez JA, Pérez-Simón JA. Barbado MV, et al. Among authors: gonzalez naranjo p. Int J Cancer. 2017 Feb 1;140(3):674-685. doi: 10.1002/ijc.30483. Epub 2016 Nov 10. Int J Cancer. 2017. PMID: 27778331 Free article.
Indazolylketones as new multitarget cannabinoid drugs.
González-Naranjo P, Pérez-Macias N, Pérez C, Roca C, Vaca G, Girón R, Sánchez-Robles E, Martín-Fontelles MI, de Ceballos ML, Martin-Requero A, Campillo NE, Páez JA. González-Naranjo P, et al. Eur J Med Chem. 2019 Mar 15;166:90-107. doi: 10.1016/j.ejmech.2019.01.030. Epub 2019 Jan 17. Eur J Med Chem. 2019. PMID: 30685536
New cannabinoid receptor antagonists as pharmacological tool.
González-Naranjo P, Pérez C, Girón R, Sánchez-Robles EM, Martín-Fontelles MI, Carrillo-López N, Martín-Vírgala J, Naves M, Campillo NE, Páez JA. González-Naranjo P, et al. Bioorg Med Chem. 2020 Oct 1;28(19):115672. doi: 10.1016/j.bmc.2020.115672. Epub 2020 Jul 29. Bioorg Med Chem. 2020. PMID: 32912440
Targeting Cannabinoid Receptor Activation and BACE-1 Activity Counteracts TgAPP Mice Memory Impairment and Alzheimer's Disease Lymphoblast Alterations.
Nuñez-Borque E, González-Naranjo P, Bartolomé F, Alquézar C, Reinares-Sebastián A, Pérez C, Ceballos ML, Páez JA, Campillo NE, Martín-Requero Á. Nuñez-Borque E, et al. Among authors: gonzalez naranjo p. Mol Neurobiol. 2020 Apr;57(4):1938-1951. doi: 10.1007/s12035-019-01813-4. Epub 2020 Jan 3. Mol Neurobiol. 2020. PMID: 31898159 Free article.
Multitarget drugs as potential therapeutic agents for alzheimer's disease. A new family of 5-substituted indazole derivatives as cholinergic and BACE1 inhibitors.
González-Naranjo P, Pérez C, González-Sánchez M, Gironda-Martínez A, Ulzurrun E, Bartolomé F, Rubio-Fernández M, Martin-Requero A, Campillo NE, Páez JA. González-Naranjo P, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2348-2356. doi: 10.1080/14756366.2022.2117315. J Enzyme Inhib Med Chem. 2022. PMID: 36050834 Free PMC article.
Novel Imidazo[4,5-c][1,2,6]thiadiazine 2,2-dioxides as antiproliferative trypanosoma cruzi drugs: Computational screening from neural network, synthesis and in vivo biological properties.
Guerra A, Gonzalez-Naranjo P, Campillo NE, Varela J, Lavaggi ML, Merlino A, Cerecetto H, González M, Gomez-Barrio A, Escario JA, Fonseca-Berzal C, Yaluf G, Paniagua-Solis J, Páez JA. Guerra A, et al. Among authors: gonzalez naranjo p. Eur J Med Chem. 2017 Aug 18;136:223-234. doi: 10.1016/j.ejmech.2017.04.075. Epub 2017 May 1. Eur J Med Chem. 2017. PMID: 28499168