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In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution.
Fischer A, Lersch R, de Andrade Krätzig N, Strong A, Friedrich MJ, Weber J, Engleitner T, Öllinger R, Yen HY, Kohlhofer U, Gonzalez-Menendez I, Sailer D, Kogan L, Lahnalampi M, Laukkanen S, Kaltenbacher T, Klement C, Rezaei M, Ammon T, Montero JJ, Schneider G, Mayerle J, Heikenwälder M, Schmidt-Supprian M, Quintanilla-Martinez L, Steiger K, Liu P, Cadiñanos J, Vassiliou GS, Saur D, Lohi O, Heinäniemi M, Conte N, Bradley A, Rad L, Rad R. Fischer A, et al. Cell Genom. 2023 Mar 8;3(3):100276. doi: 10.1016/j.xgen.2023.100276. eCollection 2023 Mar 8. Cell Genom. 2023. PMID: 36950387 Free PMC article.
Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia.
Kohl S, Zobor D, Chiang WC, Weisschuh N, Staller J, Gonzalez Menendez I, Chang S, Beck SC, Garcia Garrido M, Sothilingam V, Seeliger MW, Stanzial F, Benedicenti F, Inzana F, Héon E, Vincent A, Beis J, Strom TM, Rudolph G, Roosing S, Hollander AI, Cremers FP, Lopez I, Ren H, Moore AT, Webster AR, Michaelides M, Koenekoop RK, Zrenner E, Kaufman RJ, Tsang SH, Wissinger B, Lin JH. Kohl S, et al. Nat Genet. 2015 Jul;47(7):757-65. doi: 10.1038/ng.3319. Epub 2015 Jun 1. Nat Genet. 2015. PMID: 26029869 Free PMC article.
VA opsin-based photoreceptors in the hypothalamus of birds.
Halford S, Pires SS, Turton M, Zheng L, González-Menéndez I, Davies WL, Peirson SN, García-Fernández JM, Hankins MW, Foster RG. Halford S, et al. Curr Biol. 2009 Aug 25;19(16):1396-402. doi: 10.1016/j.cub.2009.06.066. Epub 2009 Aug 6. Curr Biol. 2009. PMID: 19664923 Free article.
Sexual behavior and testis morphology in the BACHD rat model.
Novati A, Yu-Taeger L, Gonzalez Menendez I, Quintanilla Martinez L, Nguyen HP. Novati A, et al. PLoS One. 2018 Jun 8;13(6):e0198338. doi: 10.1371/journal.pone.0198338. eCollection 2018. PLoS One. 2018. PMID: 29883458 Free PMC article.
Activated gp130 signaling selectively targets B cell differentiation to induce mature lymphoma and plasmacytoma.
Scherger AK, Al-Maarri M, Maurer HC, Schick M, Maurer S, Öllinger R, Gonzalez-Menendez I, Martella M, Thaler M, Pechloff K, Steiger K, Sander S, Ruland J, Rad R, Quintanilla-Martinez L, Wunderlich FT, Rose-John S, Keller U. Scherger AK, et al. JCI Insight. 2019 Aug 8;4(15):e128435. doi: 10.1172/jci.insight.128435. eCollection 2019 Aug 8. JCI Insight. 2019. PMID: 31391340 Free PMC article.
CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness.
Lewis R, Maurer HC, Singh N, Gonzalez-Menendez I, Wirth M, Schick M, Zhang L, Isaakidis K, Scherger AK, Schulze V, Lu J, Zenz T, Steiger K, Rad R, Quintanilla-Martinez L, Espeli M, Balabanian K, Keller U, Habringer S. Lewis R, et al. Leukemia. 2021 Oct;35(10):2895-2905. doi: 10.1038/s41375-021-01376-1. Epub 2021 Aug 6. Leukemia. 2021. PMID: 34363012 Free PMC article.
Genetic deficiency of the tumor suppressor protein p53 influences erythrocyte survival.
Bissinger R, Lang E, Gonzalez-Menendez I, Quintanilla-Martinez L, Ghashghaeinia M, Pelzl L, Sukkar B, Bhuyan AAM, Salker MS, Singh Y, Fehrenbacher B, Fakhri H, Umbach AT, Schaller M, Qadri SM, Lang F. Bissinger R, et al. Apoptosis. 2018 Dec;23(11-12):641-650. doi: 10.1007/s10495-018-1481-8. Apoptosis. 2018. PMID: 30238335
46 results