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Transfer of SCN1A to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations.
Mora-Jimenez L, Valencia M, Sanchez-Carpintero R, Tønnesen J, Fadila S, Rubinstein M, Gonzalez-Aparicio M, Bunuales M, Fernandez-Pierola E, Nicolas MJ, Puerta E, Miguelez C, Minguez PG, Lumbreras S, Gonzalez-Aseguinolaza G, Ricobaraza A, Hernandez-Alcoceba R. Mora-Jimenez L, et al. Mol Ther Nucleic Acids. 2021 Aug 19;25:585-602. doi: 10.1016/j.omtn.2021.08.003. eCollection 2021 Sep 3. Mol Ther Nucleic Acids. 2021. PMID: 34589280 Free PMC article.
Gene therapy of liver diseases.
Prieto J, Qian C, Hernandez-Alcoceba R, Gonzalez-Aseguinolaza G, Mazzolini G, Sangro B, Kramer MG. Prieto J, et al. Expert Opin Biol Ther. 2004 Jul;4(7):1073-91. doi: 10.1517/14712598.4.7.1073. Expert Opin Biol Ther. 2004. PMID: 15268675 Review.
Oxaliplatin in combination with liver-specific expression of interleukin 12 reduces the immunosuppressive microenvironment of tumours and eradicates metastatic colorectal cancer in mice.
Gonzalez-Aparicio M, Alzuguren P, Mauleon I, Medina-Echeverz J, Hervas-Stubbs S, Mancheno U, Berraondo P, Crettaz J, Gonzalez-Aseguinolaza G, Prieto J, Hernandez-Alcoceba R. Gonzalez-Aparicio M, et al. Gut. 2011 Mar;60(3):341-9. doi: 10.1136/gut.2010.211722. Epub 2010 Sep 20. Gut. 2011. PMID: 20855451 Free article.
Modulation of regulatory T-cell activity in combination with interleukin-12 increases hepatic tolerogenicity in woodchucks with chronic hepatitis B.
Otano I, Suarez L, Dotor J, Gonzalez-Aparicio M, Crettaz J, Olagüe C, Vales A, Riezu JI, Larrea E, Borras F, Benito A, Hernandez-Alcoceba R, Menne S, Prieto J, González-Aseguinolaza G. Otano I, et al. Hepatology. 2012 Aug;56(2):474-83. doi: 10.1002/hep.25667. Epub 2012 Jul 2. Hepatology. 2012. PMID: 22334260
149 results