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Synthesis of C-5a-substituted derivatives of 4-epi-isofagomine: notable β-galactosidase inhibitors and activity promotors of GM1-gangliosidosis related human lysosomal β-galactosidase mutant R201C.
Thonhofer M, Weber P, Gonzalez Santana A, Tysoe C, Fischer R, Pabst BM, Paschke E, Schalli M, Stütz AE, Tschernutter M, Windischhofer W, Withers SG. Thonhofer M, et al. Among authors: gonzalez santana a. Carbohydr Res. 2016 Jun 24;429:71-80. doi: 10.1016/j.carres.2016.03.020. Epub 2016 Mar 31. Carbohydr Res. 2016. PMID: 27063389
C-5a-substituted validamine type glycosidase inhibitors.
Schalli M, Wolfsgruber A, Gonzalez Santana A, Tysoe C, Fischer R, Stütz AE, Thonhofer M, Withers SG. Schalli M, et al. Among authors: gonzalez santana a. Carbohydr Res. 2017 Feb 22;440-441:1-9. doi: 10.1016/j.carres.2017.01.006. Epub 2017 Jan 13. Carbohydr Res. 2017. PMID: 28135569
Ligand-Directed Chemistry on Glycoside Hydrolases - A Proof of Concept Study.
Prasch H, Wolfsgruber A, Thonhofer M, Culum A, Mandl C, Weber P, Zündel M, Nasseri SA, Gonzalez Santana A, Tegl G, Nidetzky B, Gruber K, Stütz AE, Withers SG, Wrodnigg TM. Prasch H, et al. Among authors: gonzalez santana a. Chembiochem. 2023 Dec 1;24(23):e202300480. doi: 10.1002/cbic.202300480. Epub 2023 Oct 10. Chembiochem. 2023. PMID: 37715738
Young microbiota rejuvenates the aging brain.
Heijtz RD, Gonzalez-Santana A, Laman JD. Heijtz RD, et al. Among authors: gonzalez santana a. Nat Aging. 2021 Aug;1(8):625-627. doi: 10.1038/s43587-021-00100-z. Nat Aging. 2021. PMID: 37117768 No abstract available.
A glucotolerant β-glucosidase from the fungus Talaromyces amestolkiae and its conversion into a glycosynthase for glycosylation of phenolic compounds.
Méndez-Líter JA, Nieto-Domínguez M, Fernández de Toro B, González Santana A, Prieto A, Asensio JL, Cañada FJ, de Eugenio LI, Martínez MJ. Méndez-Líter JA, et al. Among authors: gonzalez santana a. Microb Cell Fact. 2020 Jun 10;19(1):127. doi: 10.1186/s12934-020-01386-1. Microb Cell Fact. 2020. PMID: 32522206 Free PMC article. Review.
16 results