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1-Aryl-1H- and 2-aryl-2H-1,2,3-triazole derivatives blockade P2X7 receptor in vitro and inflammatory response in vivo.
Gonzaga DTG, Ferreira LBG, Moreira Maramaldo Costa TE, von Ranke NL, Anastácio Furtado Pacheco P, Sposito Simões AP, Arruda JC, Dantas LP, de Freitas HR, de Melo Reis RA, Penido C, Bello ML, Castro HC, Rodrigues CR, Ferreira VF, Faria RX, da Silva FC. Gonzaga DTG, et al. Eur J Med Chem. 2017 Oct 20;139:698-717. doi: 10.1016/j.ejmech.2017.08.034. Epub 2017 Aug 16. Eur J Med Chem. 2017. PMID: 28858765
Synthetic Derivatives against Wild-Type and Non-Wild-Type Sporothrix brasiliensis: In Vitro and In Silico Analyses.
de Souza LCDSV, Alcântara LM, de Macêdo-Sales PA, Reis NF, de Oliveira DS, Machado RLD, Geraldo RB, Dos Santos ALS, Ferreira VF, Gonzaga DTG, da Silva FC, Castro HC, Baptista ARS. de Souza LCDSV, et al. Among authors: gonzaga dtg. Pharmaceuticals (Basel). 2022 Jan 1;15(1):55. doi: 10.3390/ph15010055. Pharmaceuticals (Basel). 2022. PMID: 35056112 Free PMC article.
Triazoles with inhibitory action on P2X7R impaired the acute inflammatory response in vivo and modulated the hemostatic balance in vitro and ex vivo.
Pinheiro NG, Gonzaga DTG, da Silva AR, Fuly AL, von Ranke NL, Rodrigues CR, Magalhães BQ, Pereira JS, Pacheco PAF, Silva AC, Ferreira VF, de Carvalho da Silva F, Faria RX. Pinheiro NG, et al. Among authors: gonzaga dtg. Inflamm Res. 2023 Feb;72(2):237-250. doi: 10.1007/s00011-022-01664-1. Epub 2022 Dec 3. Inflamm Res. 2023. PMID: 36463339 Free PMC article.
In vitro evaluation of 2-(1H-pyrazol-1-yl)-1,3,4-thiadiazole derivatives against replicative and infective stages of Trypanosoma cruzi.
Faria AFM, de Souza Ferreira Pereira C, Teixeira GP, Dos Santos Galvão RM, Pacheco PAF, Bello ML, de Jesus DH, Calabrese K, Gonzaga DTG, Boechat N, Faria RX. Faria AFM, et al. Among authors: gonzaga dtg. J Bioenerg Biomembr. 2023 Dec;55(6):409-421. doi: 10.1007/s10863-023-09982-7. Epub 2023 Nov 3. J Bioenerg Biomembr. 2023. PMID: 37919636
Efficient Synthesis and Antibacterial Profile of Bis(2-hydroxynaphthalene- 1,4-dione).
Novais JS, Rosandiski AC, de Carvalho CM, de Saules Silva LS, Dos S Velasco de Souza LC, Santana MV, Martins NRC, Castro HC, Ferreira VF, Gonzaga DTG, de Resende GO, de C da Silva F. Novais JS, et al. Among authors: gonzaga dtg. Curr Top Med Chem. 2020;20(2):121-131. doi: 10.2174/1568026619666191210160342. Curr Top Med Chem. 2020. PMID: 31820692
16 results