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Imaging and Molecular Annotation of Xenographs and Tumours (IMAXT): High throughput data and analysis infrastructure.
Biol Imaging. 2023 Apr 14;3:e11. doi: 10.1017/S2633903X23000090. eCollection 2023.
Biol Imaging. 2023.
PMID: 38487685
Free PMC article.
Clonal transcriptomics identifies mechanisms of chemoresistance and empowers rational design of combination therapies.
Wild SA, Cannell IG, Nicholls A, Kania K, Bressan D; CRUK IMAXT Grand Challenge Team; Hannon GJ, Sawicka K.
Wild SA, et al.
Elife. 2022 Dec 16;11:e80981. doi: 10.7554/eLife.80981.
Elife. 2022.
PMID: 36525288
Free PMC article.
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Single-cell genomic variation induced by mutational processes in cancer.
Funnell T, O'Flanagan CH, Williams MJ, McPherson A, McKinney S, Kabeer F, Lee H, Salehi S, Vázquez-García I, Shi H, Leventhal E, Masud T, Eirew P, Yap D, Zhang AW, Lim JLP, Wang B, Brimhall J, Biele J, Ting J, Au V, Van Vliet M, Liu YF, Beatty S, Lai D, Pham J, Grewal D, Abrams D, Havasov E, Leung S, Bojilova V, Moore RA, Rusk N, Uhlitz F, Ceglia N, Weiner AC, Zaikova E, Douglas JM, Zamarin D, Weigelt B, Kim SH, Da Cruz Paula A, Reis-Filho JS, Martin SD, Li Y, Xu H, de Algara TR, Lee SR, Llanos VC, Huntsman DG, McAlpine JN; IMAXT Consortium; Shah SP, Aparicio S.
Funnell T, et al.
Nature. 2022 Dec;612(7938):106-115. doi: 10.1038/s41586-022-05249-0. Epub 2022 Oct 26.
Nature. 2022.
PMID: 36289342
Free PMC article.
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Three-dimensional imaging mass cytometry for highly multiplexed molecular and cellular mapping of tissues and the tumor microenvironment.
Kuett L, Catena R, Özcan A, Plüss A; Cancer Grand Challenges IMAXT Consortium; Schraml P, Moch H, de Souza N, Bodenmiller B.
Kuett L, et al.
Nat Cancer. 2022 Jan;3(1):122-133. doi: 10.1038/s43018-021-00301-w. Epub 2021 Dec 24.
Nat Cancer. 2022.
PMID: 35121992
Free PMC article.
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Clonal fitness inferred from time-series modelling of single-cell cancer genomes.
Salehi S, Kabeer F, Ceglia N, Andronescu M, Williams MJ, Campbell KR, Masud T, Wang B, Biele J, Brimhall J, Gee D, Lee H, Ting J, Zhang AW, Tran H, O'Flanagan C, Dorri F, Rusk N, de Algara TR, Lee SR, Cheng BYC, Eirew P, Kono T, Pham J, Grewal D, Lai D, Moore R, Mungall AJ, Marra MA; IMAXT Consortium; McPherson A, Bouchard-Côté A, Aparicio S, Shah SP.
Salehi S, et al.
Nature. 2021 Jul;595(7868):585-590. doi: 10.1038/s41586-021-03648-3. Epub 2021 Jun 23.
Nature. 2021.
PMID: 34163070
Free PMC article.
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Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response.
Georgopoulou D, Callari M, Rueda OM, Shea A, Martin A, Giovannetti A, Qosaj F, Dariush A, Chin SF, Carnevalli LS, Provenzano E, Greenwood W, Lerda G, Esmaeilishirazifard E, O'Reilly M, Serra V, Bressan D; IMAXT Consortium; Mills GB, Ali HR, Cosulich SS, Hannon GJ, Bruna A, Caldas C.
Georgopoulou D, et al.
Nat Commun. 2021 Mar 31;12(1):1998. doi: 10.1038/s41467-021-22303-z.
Nat Commun. 2021.
PMID: 33790302
Free PMC article.
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Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems.
Alon S, Goodwin DR, Sinha A, Wassie AT, Chen F, Daugharthy ER, Bando Y, Kajita A, Xue AG, Marrett K, Prior R, Cui Y, Payne AC, Yao CC, Suk HJ, Wang R, Yu CJ, Tillberg P, Reginato P, Pak N, Liu S, Punthambaker S, Iyer EPR, Kohman RE, Miller JA, Lein ES, Lako A, Cullen N, Rodig S, Helvie K, Abravanel DL, Wagle N, Johnson BE, Klughammer J, Slyper M, Waldman J, Jané-Valbuena J, Rozenblatt-Rosen O, Regev A; IMAXT Consortium; Church GM, Marblestone AH, Boyden ES.
Alon S, et al.
Science. 2021 Jan 29;371(6528):eaax2656. doi: 10.1126/science.aax2656.
Science. 2021.
PMID: 33509999
Free PMC article.
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Imaging mass cytometry and multiplatform genomics define the phenogenomic landscape of breast cancer.
Ali HR, Jackson HW, Zanotelli VRT, Danenberg E, Fischer JR, Bardwell H, Provenzano E; CRUK IMAXT Grand Challenge Team; Rueda OM, Chin SF, Aparicio S, Caldas C, Bodenmiller B.
Ali HR, et al.
Nat Cancer. 2020 Feb;1(2):163-175. doi: 10.1038/s43018-020-0026-6. Epub 2020 Feb 17.
Nat Cancer. 2020.
PMID: 35122013
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