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(+)-trans-Cannabidiol-2-hydroxy pentyl is a dual CB1R antagonist/CB2R agonist that prevents diabetic nephropathy in mice.
González-Mariscal I, Carmona-Hidalgo B, Winkler M, Unciti-Broceta JD, Escamilla A, Gómez-Cañas M, Fernández-Ruiz J, Fiebich BL, Romero-Zerbo SY, Bermúdez-Silva FJ, Collado JA, Muñoz E. González-Mariscal I, et al. Pharmacol Res. 2021 Jul;169:105492. doi: 10.1016/j.phrs.2021.105492. Epub 2021 May 19. Pharmacol Res. 2021. PMID: 34019978
The Atypical Cannabinoid Abn-CBD Reduces Inflammation and Protects Liver, Pancreas, and Adipose Tissue in a Mouse Model of Prediabetes and Non-alcoholic Fatty Liver Disease.
Romero-Zerbo SY, García-Fernández M, Espinosa-Jiménez V, Pozo-Morales M, Escamilla-Sánchez A, Sánchez-Salido L, Lara E, Cobo-Vuilleumier N, Rafacho A, Olveira G, Rojo-Martínez G, Gauthier BR, González-Mariscal I, Bermúdez-Silva FJ. Romero-Zerbo SY, et al. Among authors: gonzalez mariscal i. Front Endocrinol (Lausanne). 2020 Mar 6;11:103. doi: 10.3389/fendo.2020.00103. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 32210914 Free PMC article.
Abnormal cannabidiol ameliorates inflammation preserving pancreatic beta cells in mouse models of experimental type 1 diabetes and beta cell damage.
González-Mariscal I, Pozo-Morales M, Romero-Zerbo SY, Espinosa-Jimenez V, Escamilla-Sánchez A, Sánchez-Salido L, Cobo-Vuilleumier N, Gauthier BR, Bermúdez-Silva FJ. González-Mariscal I, et al. Biomed Pharmacother. 2022 Jan;145:112361. doi: 10.1016/j.biopha.2021.112361. Epub 2021 Dec 3. Biomed Pharmacother. 2022. PMID: 34872800 Free article.
Insulin Is Transcribed and Translated in Mammalian Taste Bud Cells.
Doyle ME, Fiori JL, Gonzalez Mariscal I, Liu QR, Goodstein E, Yang H, Shin YK, Santa-Cruz Calvo S, Indig FE, Egan JM. Doyle ME, et al. Endocrinology. 2018 Sep 1;159(9):3331-3339. doi: 10.1210/en.2018-00534. Endocrinology. 2018. PMID: 30060183 Free PMC article.
Absence of cannabinoid 1 receptor in beta cells protects against high-fat/high-sugar diet-induced beta cell dysfunction and inflammation in murine islets.
González-Mariscal I, Montoro RA, Doyle ME, Liu QR, Rouse M, O'Connell JF, Santa-Cruz Calvo S, Krzysik-Walker SM, Ghosh S, Carlson OD, Lehrmann E, Zhang Y, Becker KG, Chia CW, Ghosh P, Egan JM. González-Mariscal I, et al. Diabetologia. 2018 Jun;61(6):1470-1483. doi: 10.1007/s00125-018-4576-4. Epub 2018 Mar 1. Diabetologia. 2018. PMID: 29497784 Free PMC article.
30 results