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Page 1
Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity.
Medina L, González-Lizárraga F, Dominguez-Meijide A, Ploper D, Parrales V, Sequeira S, Cima-Omori MS, Zweckstetter M, Del Bel E, Michel PP, Outeiro TF, Raisman-Vozari R, Chehín R, Socias SB. Medina L, et al. Among authors: gonzalez lizarraga f. Front Aging Neurosci. 2021 Mar 22;13:635760. doi: 10.3389/fnagi.2021.635760. eCollection 2021. Front Aging Neurosci. 2021. PMID: 33828477 Free PMC article.
Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species.
González-Lizárraga F, Socías SB, Ávila CL, Torres-Bugeau CM, Barbosa LR, Binolfi A, Sepúlveda-Díaz JE, Del-Bel E, Fernandez CO, Papy-Garcia D, Itri R, Raisman-Vozari R, Chehín RN. González-Lizárraga F, et al. Sci Rep. 2017 Feb 3;7:41755. doi: 10.1038/srep41755. Sci Rep. 2017. PMID: 28155912 Free PMC article.
Microglial glutamate release evoked by α-synuclein aggregates is prevented by dopamine.
Dos-Santos-Pereira M, Acuña L, Hamadat S, Rocca J, González-Lizárraga F, Chehín R, Sepulveda-Diaz J, Del-Bel E, Raisman-Vozari R, Michel PP. Dos-Santos-Pereira M, et al. Among authors: gonzalez lizarraga f. Glia. 2018 Nov;66(11):2353-2365. doi: 10.1002/glia.23472. Epub 2018 Nov 5. Glia. 2018. PMID: 30394585 Free article.
Rifampicin and Its Derivative Rifampicin Quinone Reduce Microglial Inflammatory Responses and Neurodegeneration Induced In Vitro by α-Synuclein Fibrillary Aggregates.
Acuña L, Hamadat S, Corbalán NS, González-Lizárraga F, Dos-Santos-Pereira M, Rocca J, Díaz JS, Del-Bel E, Papy-García D, Chehín RN, Michel PP, Raisman-Vozari R. Acuña L, et al. Among authors: gonzalez lizarraga f. Cells. 2019 Jul 25;8(8):776. doi: 10.3390/cells8080776. Cells. 2019. PMID: 31349736 Free PMC article.
Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo.
Dominguez-Meijide A, Parrales V, Vasili E, González-Lizárraga F, König A, Lázaro DF, Lannuzel A, Haik S, Del Bel E, Chehín R, Raisman-Vozari R, Michel PP, Bizat N, Outeiro TF. Dominguez-Meijide A, et al. Among authors: gonzalez lizarraga f. Neurobiol Dis. 2021 Apr;151:105256. doi: 10.1016/j.nbd.2021.105256. Epub 2021 Jan 8. Neurobiol Dis. 2021. PMID: 33429042 Free article.
The Chemically-Modified Tetracycline COL-3 and Its Parent Compound Doxycycline Prevent Microglial Inflammatory Responses by Reducing Glucose-Mediated Oxidative Stress.
Ferreira Junior NC, Dos Santos Pereira M, Francis N, Ramirez P, Martorell P, González-Lizarraga F, Figadère B, Chehin R, Del Bel E, Raisman-Vozari R, Michel PP. Ferreira Junior NC, et al. Among authors: gonzalez lizarraga f. Cells. 2021 Aug 22;10(8):2163. doi: 10.3390/cells10082163. Cells. 2021. PMID: 34440932 Free PMC article.
Neuroprotective Effects of a Novel Demeclocycline Derivative Lacking Antibiotic Activity: From a Hit to a Promising Lead Compound.
Tomas-Grau R, González-Lizárraga F, Ploper D, Avila CL, Socías SB, Besnault P, Tourville A, Mella RM, Villacé P, Salado C, Rose C, Seon-Méniel B, Brunel JM, Ferrié L, Raisman-Vozari R, Michel PP, Figadère B, Chehín R. Tomas-Grau R, et al. Among authors: gonzalez lizarraga f. Cells. 2022 Sep 4;11(17):2759. doi: 10.3390/cells11172759. Cells. 2022. PMID: 36078167 Free PMC article.
12 results