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Increased ROS generation causes apoptosis-like death: Mechanistic insights into the anti-Leishmania activity of a potent ruthenium(II) complex.
Costa MS, Gonçalves YG, Teixeira SC, Nunes DCO, Lopes DS, da Silva CV, da Silva MS, Borges BC, Silva MJB, Rodrigues RS, Rodrigues VM, Von Poelhsitz G, Yoneyama KAG. Costa MS, et al. Among authors: goncalves yg. J Inorg Biochem. 2019 Jun;195:1-12. doi: 10.1016/j.jinorgbio.2019.03.005. Epub 2019 Mar 6. J Inorg Biochem. 2019. PMID: 30861423
Ruthenium (II) complex cis-[RuII(ŋ2-O2CC7H7O2)(dppm)2]PF6-hmxbato induces ROS-mediated apoptosis in lung tumor cells producing selective cytotoxicity.
Costa MS, Gonçalves YG, Borges BC, Silva MJB, Amstalden MK, Costa TR, Antunes LMG, Rodrigues RS, Rodrigues VM, de Faria Franca E, Zoia MAP, de Araújo TG, Goulart LR, Von Poelhsitz G, Yoneyama KAG. Costa MS, et al. Among authors: goncalves yg. Sci Rep. 2020 Sep 21;10(1):15410. doi: 10.1038/s41598-020-72420-w. Sci Rep. 2020. PMID: 32958783 Free PMC article.
Organometallic Complex Strongly Impairs Chikungunya Virus Entry to the Host Cells.
de Oliveira DM, Santos IA, Martins DOS, Gonçalves YG, Cardoso-Sousa L, Sabino-Silva R, Von Poelhsitz G, Franca EF, Nicolau-Junior N, Pacca CC, Merits A, Harris M, Jardim ACG. de Oliveira DM, et al. Among authors: goncalves yg. Front Microbiol. 2020 Dec 15;11:608924. doi: 10.3389/fmicb.2020.608924. eCollection 2020. Front Microbiol. 2020. PMID: 33384677 Free PMC article.
New ruthenium(II) complexes with cyclic thio- and semicarbazone: evaluation of cytotoxicity and effects on cell migration and apoptosis of lung cancer cells.
Gonçalves YG, Becceneri AB, Graminha AE, Miranda VM, Rios RR, Rinaldi-Neto F, Costa MS, Gonçalves ACR, Deflon VM, Yoneyama KAG, Maia PIS, Franca EF, Cominetti MR, Silva RS, Von Poelhsitz G. Gonçalves YG, et al. Dalton Trans. 2023 Jul 18;52(28):9590-9606. doi: 10.1039/d3dt00750b. Dalton Trans. 2023. PMID: 37377063