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Predicted deleterious variants in ABCA1, LPL, LPA and KIF6 are associated with statin response and adverse events in patients with familial hypercholesterolemia and disturb protein structure and stability.
Dagli-Hernandez C, Ferreira GM, Freitas RCC, Borges JB, Oliveira VF, Gonçalves RM, Faludi AA, Marçal EDSR, Bastos GM, Bortolin RH, Hirata MH, Hirata RDC. Dagli-Hernandez C, et al. Among authors: goncalves rm. Pharmacogenet Genomics. 2024 Jun 1;34(4):91-104. doi: 10.1097/FPC.0000000000000524. Epub 2024 Feb 7. Pharmacogenet Genomics. 2024. PMID: 38682317
Dynamics of CD44+ bovine nucleus pulposus cells with inflammation.
Ferreira JR, Caldeira J, Sousa M, Barbosa MA, Lamghari M, Almeida-Porada G, Gonçalves RM. Ferreira JR, et al. Among authors: goncalves rm. Sci Rep. 2024 Apr 21;14(1):9156. doi: 10.1038/s41598-024-59504-7. Sci Rep. 2024. PMID: 38644369 Free PMC article.
Lipidomic analysis identified potential predictive biomarkers of statin response in subjects with Familial hypercholesterolemia.
Cerda A, Bortolin RH, Yoshinaga MY, Freitas RCC, Dagli-Hernandez C, Borges JB, Oliveira VF, Gonçalves RM, Faludi AA, Bastos GM, Hirata RDC, Hirata MH. Cerda A, et al. Among authors: goncalves rm. Chem Phys Lipids. 2023 Nov;257:105348. doi: 10.1016/j.chemphyslip.2023.105348. Epub 2023 Oct 11. Chem Phys Lipids. 2023. PMID: 37827478
LDLR and PCSK9 3´UTR variants and their putative effects on microRNA molecular interactions in familial hypercholesterolemia: a computational approach.
de Freitas RCC, Bortolin RH, Borges JB, de Oliveira VF, Dagli-Hernandez C, Marçal EDSR, Bastos GM, Gonçalves RM, Faludi AA, Silbiger VN, Luchessi AD, Hirata RDC, Hirata MH. de Freitas RCC, et al. Among authors: goncalves rm. Mol Biol Rep. 2023 Nov;50(11):9165-9177. doi: 10.1007/s11033-023-08784-9. Epub 2023 Sep 30. Mol Biol Rep. 2023. PMID: 37776414
Effects of LDLR variants rs5928, rs750518671 and rs879254797 on protein structure and functional activity in HepG2 cells transfected with CRISPR/Cas9 constructs.
Mori AA, Malaquias VB, Bonjour K, Ferreira GM, Bortolin RH, Borges JB, Oliveira VF, Gonçalves RM, Faludi AA, Bastos GM, Thurow H, Sampaio MF, Ciconelli RM, Cury AN, Fajardo CM, Hirata RDC, Hirata MH. Mori AA, et al. Among authors: goncalves rm. Gene. 2024 Jan 10;890:147821. doi: 10.1016/j.gene.2023.147821. Epub 2023 Sep 20. Gene. 2024. PMID: 37739193
Alterations of bovine nucleus pulposus cells with aging.
Molinos M, Fiordalisi MF, Caldeira J, Almeida CR, Barbosa MA, Gonçalves RM. Molinos M, et al. Among authors: goncalves rm. Aging Cell. 2023 Aug;22(8):e13873. doi: 10.1111/acel.13873. Epub 2023 May 30. Aging Cell. 2023. PMID: 37254638 Free PMC article.
149 results