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Discovery of Dual Aβ/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Drosophila Model of Alzheimer's Disease.
Gandini A, Gonçalves AE, Strocchi S, Albertini C, Janočková J, Tramarin A, Grifoni D, Poeta E, Soukup O, Muñoz-Torrero D, Monti B, Sabaté R, Bartolini M, Legname G, Bolognesi ML. Gandini A, et al. Among authors: goncalves ae. ACS Chem Neurosci. 2022 Dec 7;13(23):3314-3329. doi: 10.1021/acschemneuro.2c00357. Epub 2022 Nov 29. ACS Chem Neurosci. 2022. PMID: 36445009 Free PMC article.
Usnic acid enantiomers restore cognitive deficits and neurochemical alterations induced by Aβ1-42 in mice.
Cazarin CA, Dalmagro AP, Gonçalves AE, Boeing T, Silva LMD, Corrêa R, Klein-Júnior LC, Pinto BC, Lorenzett TS, Sobrinho TUDC, Fátima Â, Lage TCA, Fernandes SA, Souza MM. Cazarin CA, et al. Among authors: goncalves ae. Behav Brain Res. 2021 Jan 15;397:112945. doi: 10.1016/j.bbr.2020.112945. Epub 2020 Oct 3. Behav Brain Res. 2021. PMID: 33022354
Inhibitory effect of sesquiterpene lactones and the sesquiterpene alcohol aromadendrane-4β,10α-diol on memory impairment in a mouse model of Alzheimer.
Amoah SK, Dalla Vecchia MT, Pedrini B, Carnhelutti GL, Gonçalves AE, Dos Santos DA, Biavatti MW, de Souza MM. Amoah SK, et al. Among authors: goncalves ae. Eur J Pharmacol. 2015 Dec 15;769:195-202. doi: 10.1016/j.ejphar.2015.11.018. Epub 2015 Nov 24. Eur J Pharmacol. 2015. PMID: 26593432 Free article.
Structure-activity relationships of sulfonamides derived from carvacrol and their potential for the treatment of Alzheimer's disease.
de Souza MM, Andreolla MC, Ribeiro TC, Gonçalves AE, Medeiros AR, de Souza AS, Ferreira LLG, Andricopulo AD, Yunes RA, de Oliveira AS. de Souza MM, et al. Among authors: goncalves ae. RSC Med Chem. 2020 Feb 14;11(2):307-316. doi: 10.1039/d0md00009d. eCollection 2020 Feb 1. RSC Med Chem. 2020. PMID: 33479638 Free PMC article.
Neuropharmacological and acute toxicological evaluation of ethanolic extract of Allamanda cathartica L. flowers and plumieride.
Bonomini TJ, Holzmann I, Thiesen LC, Fratoni E, Muller AFF, Lucinda-Silva RM, Yunes RA, Malheiros A, Gonçalves AE, Dalmagro AP, da Silva KABS, de Souza MM, Santin JR. Bonomini TJ, et al. Among authors: goncalves ae. Regul Toxicol Pharmacol. 2017 Dec;91:9-19. doi: 10.1016/j.yrtph.2017.10.005. Epub 2017 Oct 4. Regul Toxicol Pharmacol. 2017. PMID: 28986178
26 results