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CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart.
Gomez-Velazquez M, Badia-Careaga C, Lechuga-Vieco AV, Nieto-Arellano R, Tena JJ, Rollan I, Alvarez A, Torroja C, Caceres EF, Roy AR, Galjart N, Delgado-Olguin P, Sanchez-Cabo F, Enriquez JA, Gomez-Skarmeta JL, Manzanares M. Gomez-Velazquez M, et al. PLoS Genet. 2017 Aug 28;13(8):e1006985. doi: 10.1371/journal.pgen.1006985. eCollection 2017 Aug. PLoS Genet. 2017. PMID: 28846746 Free PMC article.
Odd-skipped genes encode repressors that control kidney development.
Tena JJ, Neto A, de la Calle-Mustienes E, Bras-Pereira C, Casares F, Gómez-Skarmeta JL. Tena JJ, et al. Dev Biol. 2007 Jan 15;301(2):518-31. doi: 10.1016/j.ydbio.2006.08.063. Epub 2006 Sep 1. Dev Biol. 2007. PMID: 17011543 Free article.
Understanding the regulatory genome.
Alonso ME, Pernaute B, Crespo M, Gómez-Skarmeta JL, Manzanares M. Alonso ME, et al. Int J Dev Biol. 2009;53(8-10):1367-78. doi: 10.1387/ijdb.072428ma. Int J Dev Biol. 2009. PMID: 19247937 Free article. Review.
Multiple enhancers located in a 1-Mb region upstream of POU3F4 promote expression during inner ear development and may be required for hearing.
Naranjo S, Voesenek K, de la Calle-Mustienes E, Robert-Moreno A, Kokotas H, Grigoriadou M, Economides J, Van Camp G, Hilgert N, Moreno F, Alsina B, Petersen MB, Kremer H, Gómez-Skarmeta JL. Naranjo S, et al. Hum Genet. 2010 Oct;128(4):411-9. doi: 10.1007/s00439-010-0864-x. Epub 2010 Jul 29. Hum Genet. 2010. PMID: 20668882 Free PMC article.
Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus.
Kouwenhoven EN, van Heeringen SJ, Tena JJ, Oti M, Dutilh BE, Alonso ME, de la Calle-Mustienes E, Smeenk L, Rinne T, Parsaulian L, Bolat E, Jurgelenaite R, Huynen MA, Hoischen A, Veltman JA, Brunner HG, Roscioli T, Oates E, Wilson M, Manzanares M, Gómez-Skarmeta JL, Stunnenberg HG, Lohrum M, van Bokhoven H, Zhou H. Kouwenhoven EN, et al. PLoS Genet. 2010 Aug 19;6(8):e1001065. doi: 10.1371/journal.pgen.1001065. PLoS Genet. 2010. PMID: 20808887 Free PMC article.
Allelic variation at the 8q23.3 colorectal cancer risk locus functions as a cis-acting regulator of EIF3H.
Pittman AM, Naranjo S, Jalava SE, Twiss P, Ma Y, Olver B, Lloyd A, Vijayakrishnan J, Qureshi M, Broderick P, van Wezel T, Morreau H, Tuupanen S, Aaltonen LA, Alonso ME, Manzanares M, Gavilán A, Visakorpi T, Gómez-Skarmeta JL, Houlston RS. Pittman AM, et al. PLoS Genet. 2010 Sep 16;6(9):e1001126. doi: 10.1371/journal.pgen.1001126. PLoS Genet. 2010. PMID: 20862326 Free PMC article.
142 results