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Page 1
Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting.
Capelo-Diz A, Lachiondo-Ortega S, Fernández-Ramos D, Cañas-Martín J, Goikoetxea-Usandizaga N, Serrano-Maciá M, González-Rellan MJ, Mosca L, Blazquez-Vicens J, Tinahones-Ruano A, Fondevila MF, Buyan M, Delgado TC, Gutierrez de Juan V, Ayuso-García P, Sánchez-Rueda A, Velasco-Avilés S, Fernández-Susavila H, Riobello-Suárez C, Dziechciarz B, Montiel-Duarte C, Lopitz-Otsoa F, Bizkarguenaga M, Bilbao-García J, Bernardo-Seisdedos G, Senra A, Soriano-Navarro M, Millet O, Díaz-Lagares Á, Crujeiras AB, Bao-Caamano A, Cabrera D, van Liempd S, Tamayo-Carro M, Borzacchiello L, Gomez-Santos B, Buqué X, Sáenz de Urturi D, González-Romero F, Simon J, Rodríguez-Agudo R, Ruiz A, Matute C, Beiroa D, Falcon-Perez JM, Aspichueta P, Rodríguez-Cuesta J, Porcelli M, Pajares MA, Ameneiro C, Fidalgo M, Aransay AM, Lama-Díaz T, Blanco MG, López M, Villa-Bellosta R, Müller TD, Nogueiras R, Woodhoo A, Martínez-Chantar ML, Varela-Rey M. Capelo-Diz A, et al. Among authors: gomez santos b. Cell Metab. 2023 Aug 8;35(8):1373-1389.e8. doi: 10.1016/j.cmet.2023.07.002. Epub 2023 Jul 31. Cell Metab. 2023. PMID: 37527658 Free PMC article.
Protective effects of the succinate/SUCNR1 axis on damaged hepatocytes in NAFLD.
Marsal-Beltran A, Rodríguez-Castellano A, Astiarraga B, Calvo E, Rada P, Madeira A, Rodríguez-Peña MM, Llauradó G, Núñez-Roa C, Gómez-Santos B, Maymó-Masip E, Bosch R, Frutos MD, Moreno-Navarrete JM, Ramos-Molina B, Aspichueta P, Joven J, Fernández-Real JM, Quer JC, Valverde ÁM, Pardo A, Vendrell J, Ceperuelo-Mallafré V, Fernández-Veledo S. Marsal-Beltran A, et al. Among authors: gomez santos b. Metabolism. 2023 Aug;145:155630. doi: 10.1016/j.metabol.2023.155630. Epub 2023 Jun 13. Metabolism. 2023. PMID: 37315889 Free article.
In Vivo Tissue Lipid Uptake in Antisense Oligonucleotide (ASO)-Treated Mice.
Aurrekoetxea I, Gomez-Santos B, Apodaka-Biguri M, Ruiz de Gauna M, Gonzalez-Romero F, Buqué X, Aspichueta P. Aurrekoetxea I, et al. Among authors: gomez santos b. Methods Mol Biol. 2023;2675:1-13. doi: 10.1007/978-1-0716-3247-5_1. Methods Mol Biol. 2023. PMID: 37258751
Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis.
Sáenz de Urturi D, Buqué X, Porteiro B, Folgueira C, Mora A, Delgado TC, Prieto-Fernández E, Olaizola P, Gómez-Santos B, Apodaka-Biguri M, González-Romero F, Nieva-Zuluaga A, Ruiz de Gauna M, Goikoetxea-Usandizaga N, García-Rodríguez JL, Gutierrez de Juan V, Aurrekoetxea I, Montalvo-Romeral V, Novoa EM, Martín-Guerrero I, Varela-Rey M, Bhanot S, Lee R, Banales JM, Syn WK, Sabio G, Martínez-Chantar ML, Nogueiras R, Aspichueta P. Sáenz de Urturi D, et al. Among authors: gomez santos b. Nat Commun. 2022 Mar 1;13(1):1096. doi: 10.1038/s41467-022-28749-z. Nat Commun. 2022. PMID: 35232994 Free PMC article.
Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids.
Ruiz de Gauna M, Biancaniello F, González-Romero F, Rodrigues PM, Lapitz A, Gómez-Santos B, Olaizola P, Di Matteo S, Aurrekoetxea I, Labiano I, Nieva-Zuluaga A, Benito-Vicente A, Perugorria MJ, Apodaka-Biguri M, Paiva NA, Sáenz de Urturi D, Buqué X, Delgado I, Martín C, Azkargorta M, Elortza F, Calvisi DF, Andersen JB, Alvaro D, Cardinale V, Bujanda L, Banales JM, Aspichueta P. Ruiz de Gauna M, et al. Among authors: gomez santos b. Hepatology. 2022 Dec;76(6):1617-1633. doi: 10.1002/hep.32344. Epub 2022 Feb 8. Hepatology. 2022. PMID: 35030285 Free PMC article.
Fat: Quality, or Quantity? What Matters Most for the Progression of Metabolic Associated Fatty Liver Disease (MAFLD).
Estévez-Vázquez O, Benedé-Ubieto R, Guo F, Gómez-Santos B, Aspichueta P, Reissing J, Bruns T, Sanz-García C, Sydor S, Bechmann LP, Maranillo E, Sañudo JR, Vázquez MT, Lamas-Paz A, Morán L, Mazariegos MS, Ciudin A, Pericàs JM, Peligros MI, Vaquero J, Martínez-Naves E, Liedtke C, Regueiro JR, Trautwein C, Bañares R, Cubero FJ, Nevzorova YA. Estévez-Vázquez O, et al. Among authors: gomez santos b. Biomedicines. 2021 Sep 22;9(10):1289. doi: 10.3390/biomedicines9101289. Biomedicines. 2021. PMID: 34680405 Free PMC article.
E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment.
González-Romero F, Mestre D, Aurrekoetxea I, O'Rourke CJ, Andersen JB, Woodhoo A, Tamayo-Caro M, Varela-Rey M, Palomo-Irigoyen M, Gómez-Santos B, de Urturi DS, Núñez-García M, García-Rodríguez JL, Fernández-Ares L, Buqué X, Iglesias-Ara A, Bernales I, De Juan VG, Delgado TC, Goikoetxea-Usandizaga N, Lee R, Bhanot S, Delgado I, Perugorria MJ, Errazti G, Mosteiro L, Gaztambide S, Martinez de la Piscina I, Iruzubieta P, Crespo J, Banales JM, Martínez-Chantar ML, Castaño L, Zubiaga AM, Aspichueta P. González-Romero F, et al. Among authors: gomez santos b. Cancer Res. 2021 Jun 1;81(11):2874-2887. doi: 10.1158/0008-5472.CAN-20-2052. Epub 2021 Mar 26. Cancer Res. 2021. PMID: 33771899
Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH.
Simón J, Goikoetxea-Usandizaga N, Serrano-Maciá M, Fernández-Ramos D, Sáenz de Urturi D, Gruskos JJ, Fernández-Tussy P, Lachiondo-Ortega S, González-Recio I, Rodríguez-Agudo R, Gutiérrez-de-Juan V, Rodríguez-Iruretagoyena B, Varela-Rey M, Gimenez-Mascarell P, Mercado-Gomez M, Gómez-Santos B, Fernandez-Rodriguez C, Lopitz-Otsoa F, Bizkarguenaga M, Dames S, Schaeper U, Martin F, Sabio G, Iruzubieta P, Crespo J, Aspichueta P, Chu KH, Buccella D, Martín C, Delgado TC, Martínez-Cruz LA, Martínez-Chantar ML. Simón J, et al. Among authors: gomez santos b. J Hepatol. 2021 Jul;75(1):34-45. doi: 10.1016/j.jhep.2021.01.043. Epub 2021 Feb 9. J Hepatol. 2021. PMID: 33571553 Free PMC article.
Liver osteopontin is required to prevent the progression of age-related nonalcoholic fatty liver disease.
Gómez-Santos B, Saenz de Urturi D, Nuñez-García M, Gonzalez-Romero F, Buque X, Aurrekoetxea I, Gutiérrez de Juan V, Gonzalez-Rellan MJ, García-Monzón C, González-Rodríguez Á, Mosteiro L, Errazti G, Mifsut P, Gaztambide S, Castaño L, Martin C, Nogueiras R, Martinez-Chantar ML, Syn WK, Aspichueta P. Gómez-Santos B, et al. Aging Cell. 2020 Aug;19(8):e13183. doi: 10.1111/acel.13183. Epub 2020 Jul 7. Aging Cell. 2020. PMID: 32638492 Free PMC article.
16 results