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A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques.
Tran KM, Kawauchi S, Kramár EA, Rezaie N, Liang HY, Sakr JS, Gomez-Arboledas A, Arreola MA, Cunha CD, Phan J, Wang S, Collins S, Walker A, Shi KX, Neumann J, Filimban G, Shi Z, Milinkeviciute G, Javonillo DI, Tran K, Gantuz M, Forner S, Swarup V, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, MacGregor GR, Green KN. Tran KM, et al. Among authors: gomez arboledas a. Mol Neurodegener. 2023 Feb 17;18(1):12. doi: 10.1186/s13024-023-00598-4. Mol Neurodegener. 2023. PMID: 36803190 Free PMC article.
Astrocytes: From the Physiology to the Disease.
Trujillo-Estrada L, Gomez-Arboledas A, Forner S, Martini AC, Gutierrez A, Baglietto-Vargas D, LaFerla FM. Trujillo-Estrada L, et al. Curr Alzheimer Res. 2019;16(8):675-698. doi: 10.2174/1567205016666190830110152. Curr Alzheimer Res. 2019. PMID: 31470787 Review.
Amyloid-beta impairs TOM1-mediated IL-1R1 signaling.
Martini AC, Gomez-Arboledas A, Forner S, Rodriguez-Ortiz CJ, McQuade A, Danhash E, Phan J, Javonillo D, Ha JV, Tram M, Trujillo-Estrada L, da Cunha C, Ager RR, Davila JC, Kitazawa M, Blurton-Jones M, Gutierrez A, Baglietto-Vargas D, Medeiros R, LaFerla FM. Martini AC, et al. Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21198-21206. doi: 10.1073/pnas.1914088116. Epub 2019 Sep 30. Proc Natl Acad Sci U S A. 2019. PMID: 31570577 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35109299
Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease.
Javonillo DI, Tran KM, Phan J, Hingco E, Kramár EA, da Cunha C, Forner S, Kawauchi S, Milinkeviciute G, Gomez-Arboledas A, Neumann J, Banh CE, Huynh M, Matheos DP, Rezaie N, Alcantara JA, Mortazavi A, Wood MA, Tenner AJ, MacGregor GR, Green KN, LaFerla FM. Javonillo DI, et al. Front Neurosci. 2022 Jan 24;15:785276. doi: 10.3389/fnins.2021.785276. eCollection 2021. Front Neurosci. 2022. PMID: 35140584 Free PMC article.
Modulation of C5a-C5aR1 signaling alters the dynamics of AD progression.
Carvalho K, Schartz ND, Balderrama-Gutierrez G, Liang HY, Chu SH, Selvan P, Gomez-Arboledas A, Petrisko TJ, Fonseca MI, Mortazavi A, Tenner AJ. Carvalho K, et al. Among authors: gomez arboledas a. J Neuroinflammation. 2022 Jul 11;19(1):178. doi: 10.1186/s12974-022-02539-2. J Neuroinflammation. 2022. PMID: 35820938 Free PMC article.
Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer's disease.
Baglietto-Vargas D, Sánchez-Mejias E, Navarro V, Jimenez S, Trujillo-Estrada L, Gómez-Arboledas A, Sánchez-Mico M, Sánchez-Varo R, Vizuete M, Dávila JC, García-Verdugo JM, Vitorica J, Gutierrez A. Baglietto-Vargas D, et al. Sci Rep. 2017 Aug 30;7(1):10085. doi: 10.1038/s41598-017-10353-7. Sci Rep. 2017. PMID: 28855626 Free PMC article.
24 results