Gomez DE - Search Results

1

Preclinical Efficacy and Toxicology Evaluation of RAC1 Inhibitor 1A-116 in Human Glioblastoma Models.

Cardama GA, Maggio J, Valdez Capuccino L, Gonzalez N, Matiller V, Ortega HH, Perez GR, Demarco IA, Spitzer E, Gomez DE, Lorenzano Menna P, Alonso DF. Cardama GA, et al. Among authors: gomez de. Cancers (Basel). 2022 Sep 30;14(19):4810. doi: 10.3390/cancers14194810. Cancers (Basel). 2022. PMID: 36230732 Free PMC article.

2

[Rho GTPases as therapeutic targets in cancer and other human diseases].

Lorenzano Menna P, Cardama GA, Comin MJ, Alonso DF, Gómez DE. Lorenzano Menna P, et al. Among authors: gomez de. Medicina (B Aires). 2010;70(6):555-64. Medicina (B Aires). 2010. PMID: 21163747 Review. Spanish.

3

AZT as a telomerase inhibitor.

Gomez DE, Armando RG, Alonso DF. Gomez DE, et al. Front Oncol. 2012 Sep 6;2:113. doi: 10.3389/fonc.2012.00113. eCollection 2012. Front Oncol. 2012. PMID: 22973556 Free PMC article.

4

Preclinical development of novel Rac1-GEF signaling inhibitors using a rational design approach in highly aggressive breast cancer cell lines.

Cardama GA, Comin MJ, Hornos L, Gonzalez N, Defelipe L, Turjanski AG, Alonso DF, Gomez DE, Menna PL. Cardama GA, et al. Among authors: gomez de. Anticancer Agents Med Chem. 2014;14(6):840-51. doi: 10.2174/18715206113136660334. Anticancer Agents Med Chem. 2014. PMID: 24066799 Free PMC article.

5

Proapoptotic and antiinvasive activity of Rac1 small molecule inhibitors on malignant glioma cells.

Cardama GA, Gonzalez N, Ciarlantini M, Gandolfi Donadío L, Comin MJ, Alonso DF, Menna PL, Gomez DE. Cardama GA, et al. Among authors: gomez de. Onco Targets Ther. 2014 Oct 30;7:2021-33. doi: 10.2147/OTT.S67998. eCollection 2014. Onco Targets Ther. 2014. PMID: 25378937 Free PMC article.

6

[Rho GTPases as molecular targets in cancer. Strategies and therapeutic opportunities].

Maggio J, González N, Cardama GA, Gomez DE. Maggio J, et al. Among authors: gomez de. Medicina (B Aires). 2017;77(6):497-504. Medicina (B Aires). 2017. PMID: 29223942 Free article. Review. Spanish.

7

Computational and in vitro Pharmacodynamics Characterization of 1A-116 Rac1 Inhibitor: Relevance of Trp56 in Its Biological Activity.

González N, Cardama GA, Chinestrad P, Robles-Valero J, Rodríguez-Fdez S, Lorenzo-Martín LF, Bustelo XR, Lorenzano Menna P, Gomez DE. González N, et al. Among authors: gomez de. Front Cell Dev Biol. 2020 Apr 15;8:240. doi: 10.3389/fcell.2020.00240. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 32351958 Free PMC article.

8

Rho GTPases as therapeutic targets in cancer (Review).

Cardama GA, Gonzalez N, Maggio J, Menna PL, Gomez DE. Cardama GA, et al. Among authors: gomez de. Int J Oncol. 2017 Oct;51(4):1025-1034. doi: 10.3892/ijo.2017.4093. Epub 2017 Aug 9. Int J Oncol. 2017. PMID: 28848995 Free PMC article. Review.

9

Preclinical evaluation of racotumomab, an anti-idiotype monoclonal antibody to N-glycolyl-containing gangliosides, with or without chemotherapy in a mouse model of non-small cell lung cancer.

Segatori VI, Vazquez AM, Gomez DE, Gabri MR, Alonso DF. Segatori VI, et al. Among authors: gomez de. Front Oncol. 2012 Nov 8;2:160. doi: 10.3389/fonc.2012.00160. eCollection 2012. Front Oncol. 2012. PMID: 23162791 Free PMC article.

10

The novel desmopressin analogue [V4Q5]dDAVP inhibits angiogenesis, tumour growth and metastases in vasopressin type 2 receptor-expressing breast cancer models.

Garona J, Pifano M, Orlando UD, Pastrian MB, Iannucci NB, Ortega HH, Podesta EJ, Gomez DE, Ripoll GV, Alonso DF. Garona J, et al. Among authors: gomez de. Int J Oncol. 2015;46(6):2335-45. doi: 10.3892/ijo.2015.2952. Epub 2015 Apr 3. Int J Oncol. 2015. PMID: 25846632 Free PMC article.

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