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EPAC1 inhibition protects the heart from doxorubicin-induced toxicity.
Mazevet M, Belhadef A, Ribeiro M, Dayde D, Llach A, Laudette M, Belleville T, Mateo P, Gressette M, Lefebvre F, Chen J, Bachelot-Loza C, Rucker-Martin C, Lezoualch F, Crozatier B, Benitah JP, Vozenin MC, Fischmeister R, Gomez AM, Lemaire C, Morel E. Mazevet M, et al. Among authors: gomez am. Elife. 2023 Aug 8;12:e83831. doi: 10.7554/eLife.83831. Elife. 2023. PMID: 37551870 Free PMC article.
The cAMP binding protein Epac modulates Ca2+ sparks by a Ca2+/calmodulin kinase signalling pathway in rat cardiac myocytes.
Pereira L, Métrich M, Fernández-Velasco M, Lucas A, Leroy J, Perrier R, Morel E, Fischmeister R, Richard S, Bénitah JP, Lezoualc'h F, Gómez AM. Pereira L, et al. Among authors: gomez am. J Physiol. 2007 Sep 1;583(Pt 2):685-94. doi: 10.1113/jphysiol.2007.133066. Epub 2007 Jun 28. J Physiol. 2007. PMID: 17599964 Free PMC article.
Conditional FKBP12.6 overexpression in mouse cardiac myocytes prevents triggered ventricular tachycardia through specific alterations in excitation-contraction coupling.
Gellen B, Fernández-Velasco M, Briec F, Vinet L, LeQuang K, Rouet-Benzineb P, Bénitah JP, Pezet M, Palais G, Pellegrin N, Zhang A, Perrier R, Escoubet B, Marniquet X, Richard S, Jaisser F, Gómez AM, Charpentier F, Mercadier JJ. Gellen B, et al. Among authors: gomez am. Circulation. 2008 Apr 8;117(14):1778-86. doi: 10.1161/CIRCULATIONAHA.107.731893. Epub 2008 Mar 31. Circulation. 2008. PMID: 18378612
Increased Ca2+ sensitivity of the ryanodine receptor mutant RyR2R4496C underlies catecholaminergic polymorphic ventricular tachycardia.
Fernández-Velasco M, Rueda A, Rizzi N, Benitah JP, Colombi B, Napolitano C, Priori SG, Richard S, Gómez AM. Fernández-Velasco M, et al. Among authors: gomez am. Circ Res. 2009 Jan 30;104(2):201-9, 12p following 209. doi: 10.1161/CIRCRESAHA.108.177493. Epub 2008 Dec 18. Circ Res. 2009. PMID: 19096022 Free PMC article.
Mineralocorticoid modulation of cardiac ryanodine receptor activity is associated with downregulation of FK506-binding proteins.
Gómez AM, Rueda A, Sainte-Marie Y, Pereira L, Zissimopoulos S, Zhu X, Schaub R, Perrier E, Perrier R, Latouche C, Richard S, Picot MC, Jaisser F, Lai FA, Valdivia HH, Benitah JP. Gómez AM, et al. Circulation. 2009 Apr 28;119(16):2179-87. doi: 10.1161/CIRCULATIONAHA.108.805804. Epub 2009 Apr 13. Circulation. 2009. PMID: 19364981 Free article.
460 results