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Synthesis, anticancer activity and mechanism of action of new thiazole derivatives.
Eur J Med Chem. 2018 Jan 20;144:874-886. doi: 10.1016/j.ejmech.2017.12.040. Epub 2017 Dec 14.
Eur J Med Chem. 2018.
PMID: 29329071
Phthalimido-thiazoles as building blocks and their effects on the growth and morphology of Trypanosoma cruzi.
Gomes PA, Oliveira AR, Cardoso MV, Santiago Ede F, Barbosa Mde O, de Siqueira LR, Moreira DR, Bastos TM, Brayner FA, Soares MB, Mendes AP, de Castro MC, Pereira VR, Leite AC.
Gomes PA, et al.
Eur J Med Chem. 2016 Mar 23;111:46-57. doi: 10.1016/j.ejmech.2016.01.010. Epub 2016 Jan 11.
Eur J Med Chem. 2016.
PMID: 26854377
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Antitumor and immunomodulatory activities of thiosemicarbazones and 1,3-Thiazoles in Jurkat and HT-29 cells.
Dos Santos TA, da Silva AC, Silva EB, Gomes PA, Espíndola JW, Cardoso MV, Moreira DR, Leite AC, Pereira VR.
Dos Santos TA, et al.
Biomed Pharmacother. 2016 Aug;82:555-60. doi: 10.1016/j.biopha.2016.05.038. Epub 2016 Jun 6.
Biomed Pharmacother. 2016.
PMID: 27470396
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Thiazolyl-isatin derivatives: Synthesis, in silico studies, in vitro biological profile against breast cancer cells, mRNA expression, P-gp modulation, and interactions of Akt2 and VIM proteins.
Freitas LAB, Sousa C, Lima BS, Duarte D, Gomes PATM, Ramos CGC, Costa VCM, Pitta MGDR, Rêgo MJBM, de Simone CA, Videira M, Leite ACL.
Freitas LAB, et al. Among authors: gomes patm.
Chem Biol Interact. 2024 May 1;394:110954. doi: 10.1016/j.cbi.2024.110954. Epub 2024 Mar 20.
Chem Biol Interact. 2024.
PMID: 38518852
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Anti-inflammatory and antinociceptive effects of the isatin derivative (Z)-2-(5-chloro-2-oxoindolin-3-ylidene)-N-phenyl-hydrazinecarbothioamide in mice.
Dantas LLSFR, Fonseca AG, Pereira JR, Furtado AA, Gomes PATM, Fernandes-Pedrosa MF, Leite ACL, Rêgo MJBM, Pitta MGR, Lemos TMAM.
Dantas LLSFR, et al. Among authors: gomes patm.
Braz J Med Biol Res. 2020;53(10):e10204. doi: 10.1590/1414-431X202010204. Epub 2020 Sep 7.
Braz J Med Biol Res. 2020.
PMID: 32901685
Free PMC article.
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