Gomes AR - Search Results

1

Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancer.

Chen J, Gomes AR, Monteiro LJ, Wong SY, Wu LH, Ng TT, Karadedou CT, Millour J, Ip YC, Cheung YN, Sunters A, Chan KY, Lam EW, Khoo US. Chen J, et al. Among authors: gomes ar. PLoS One. 2010 Aug 20;5(8):e12293. doi: 10.1371/journal.pone.0012293. PLoS One. 2010. PMID: 20808831 Free PMC article.

2

FOXO3a represses VEGF expression through FOXM1-dependent and -independent mechanisms in breast cancer.

Karadedou CT, Gomes AR, Chen J, Petkovic M, Ho KK, Zwolinska AK, Feltes A, Wong SY, Chan KY, Cheung YN, Tsang JW, Brosens JJ, Khoo US, Lam EW. Karadedou CT, et al. Among authors: gomes ar. Oncogene. 2012 Apr 5;31(14):1845-58. doi: 10.1038/onc.2011.368. Epub 2011 Aug 22. Oncogene. 2012. PMID: 21860419 Free PMC article.

3

FOXM1 targets NBS1 to regulate DNA damage-induced senescence and epirubicin resistance.

Khongkow P, Karunarathna U, Khongkow M, Gong C, Gomes AR, Yagüe E, Monteiro LJ, Kongsema M, Zona S, Man EP, Tsang JW, Coombes RC, Wu KJ, Khoo US, Medema RH, Freire R, Lam EW. Khongkow P, et al. Among authors: gomes ar. Oncogene. 2014 Aug 7;33(32):4144-55. doi: 10.1038/onc.2013.457. Epub 2013 Oct 21. Oncogene. 2014. PMID: 24141789 Free PMC article.

4

FOXA1 repression is associated with loss of BRCA1 and increased promoter methylation and chromatin silencing in breast cancer.

Gong C, Fujino K, Monteiro LJ, Gomes AR, Drost R, Davidson-Smith H, Takeda S, Khoo US, Jonkers J, Sproul D, Lam EW. Gong C, et al. Among authors: gomes ar. Oncogene. 2015 Sep 24;34(39):5012-24. doi: 10.1038/onc.2014.421. Epub 2014 Dec 22. Oncogene. 2015. PMID: 25531315 Free PMC article.

5

Paclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance.

Khongkow P, Gomes AR, Gong C, Man EP, Tsang JW, Zhao F, Monteiro LJ, Coombes RC, Medema RH, Khoo US, Lam EW. Khongkow P, et al. Among authors: gomes ar. Oncogene. 2016 Feb 25;35(8):990-1002. doi: 10.1038/onc.2015.152. Epub 2015 May 11. Oncogene. 2016. PMID: 25961928 Free PMC article.

6

Forkhead box K2 modulates epirubicin and paclitaxel sensitivity through FOXO3a in breast cancer.

Nestal de Moraes G, Khongkow P, Gong C, Yao S, Gomes AR, Ji Z, Kandola N, Delbue D, Man EP, Khoo US, Sharrocks AD, Lam EW. Nestal de Moraes G, et al. Among authors: gomes ar. Oncogenesis. 2015 Sep 7;4(9):e167. doi: 10.1038/oncsis.2015.26. Oncogenesis. 2015. PMID: 26344694 Free PMC article.

7

Correction: FOXO3a represses VEGF expression through FOXM1-dependent and -independent mechanisms in breast cancer.

Karadedou CT, Gomes AR, Chen J, Petkovic M, Ho KK, Zwolinska AK, Feltes A, Wong SY, Chan KYK, Cheung YN, Tsang JWH, Brosens JJ, Khoo US, Lam EW. Karadedou CT, et al. Among authors: gomes ar. Oncogene. 2019 Jun;38(25):5111-5112. doi: 10.1038/s41388-019-0770-1. Oncogene. 2019. PMID: 30867566 Free article.

8

The forkhead transcription factor FOXO3a increases phosphoinositide-3 kinase/Akt activity in drug-resistant leukemic cells through induction of PIK3CA expression.

Hui RC, Gomes AR, Constantinidou D, Costa JR, Karadedou CT, Fernandez de Mattos S, Wymann MP, Brosens JJ, Schulze A, Lam EW. Hui RC, et al. Among authors: gomes ar. Mol Cell Biol. 2008 Oct;28(19):5886-98. doi: 10.1128/MCB.01265-07. Epub 2008 Jul 21. Mol Cell Biol. 2008. PMID: 18644865 Free PMC article.

9

Phosphorylation of FOXO3a on Ser-7 by p38 promotes its nuclear localization in response to doxorubicin.

Ho KK, McGuire VA, Koo CY, Muir KW, de Olano N, Maifoshie E, Kelly DJ, McGovern UB, Monteiro LJ, Gomes AR, Nebreda AR, Campbell DG, Arthur JS, Lam EW. Ho KK, et al. Among authors: gomes ar. J Biol Chem. 2012 Jan 6;287(2):1545-55. doi: 10.1074/jbc.M111.284224. Epub 2011 Nov 29. J Biol Chem. 2012. PMID: 22128155 Free PMC article.

10

SIRT6 modulates paclitaxel and epirubicin resistance and survival in breast cancer.

Khongkow M, Olmos Y, Gong C, Gomes AR, Monteiro LJ, Yagüe E, Cavaco TB, Khongkow P, Man EP, Laohasinnarong S, Koo CY, Harada-Shoji N, Tsang JW, Coombes RC, Schwer B, Khoo US, Lam EW. Khongkow M, et al. Among authors: gomes ar. Carcinogenesis. 2013 Jul;34(7):1476-86. doi: 10.1093/carcin/bgt098. Epub 2013 Mar 20. Carcinogenesis. 2013. PMID: 23514751

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