Gomaa HAM - Search Results

1

New 1,2,4-oxadiazole/pyrrolidine hybrids as topoisomerase IV and DNA gyrase inhibitors with promising antibacterial activity.

Frejat FOA, Cao Y, Wang L, Zhai H, Abdelazeem AH, Gomaa HAM, Youssif BGM, Wu C. Frejat FOA, et al. Among authors: gomaa ham. Arch Pharm (Weinheim). 2022 Jul;355(7):e2100516. doi: 10.1002/ardp.202100516. Epub 2022 Apr 1. Arch Pharm (Weinheim). 2022. PMID: 35363388

2

Novel aryl carboximidamide and 3-aryl-1,2,4-oxadiazole analogues of naproxen as dual selective COX-2/15-LOX inhibitors: Design, synthesis and docking studies.

Youssif BGM, Mohamed MFA, Al-Sanea MM, Moustafa AH, Abdelhamid AA, Gomaa HAM. Youssif BGM, et al. Among authors: gomaa ham. Bioorg Chem. 2019 Apr;85:577-584. doi: 10.1016/j.bioorg.2019.02.043. Epub 2019 Feb 20. Bioorg Chem. 2019. PMID: 30878890

3

5-Chlorobenzofuran-2-carboxamides: From allosteric CB1 modulators to potential apoptotic antitumor agents.

Youssif BGM, Mohamed AM, Osman EEA, Abou-Ghadir OF, Elnaggar DH, Abdelrahman MH, Treamblu L, Gomaa HAM. Youssif BGM, et al. Among authors: gomaa ham. Eur J Med Chem. 2019 Sep 1;177:1-11. doi: 10.1016/j.ejmech.2019.05.040. Epub 2019 May 16. Eur J Med Chem. 2019. PMID: 31128433

4

Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety.

Al-Sanea MM, Gotina L, Mohamed MF, Grace Thomas Parambi D, Gomaa HAM, Mathew B, Youssif BGM, Alharbi KS, Elsayed ZM, Abdelgawad MA, Eldehna WM. Al-Sanea MM, et al. Among authors: gomaa ham. Drug Des Devel Ther. 2020 Feb 4;14:497-508. doi: 10.2147/DDDT.S237957. eCollection 2020. Drug Des Devel Ther. 2020. PMID: 32103894 Free PMC article.

5

Novel 1,2,4-triazole derivatives as apoptotic inducers targeting p53: Synthesis and antiproliferative activity.

Gomaa HAM, El-Sherief HAM, Hussein S, Gouda AM, Salem OIA, Alharbi KS, Hayallah AM, Youssif BGM. Gomaa HAM, et al. Bioorg Chem. 2020 Dec;105:104369. doi: 10.1016/j.bioorg.2020.104369. Epub 2020 Oct 12. Bioorg Chem. 2020. PMID: 33091670

6

Design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives bearing 1,3-thiazole moiety as novel anti-inflammatory EGFR inhibitors with cardiac safety profile.

Abdel-Aziz SA, Taher ES, Lan P, Asaad GF, Gomaa HAM, El-Koussi NA, Youssif BGM. Abdel-Aziz SA, et al. Among authors: gomaa ham. Bioorg Chem. 2021 Jun;111:104890. doi: 10.1016/j.bioorg.2021.104890. Epub 2021 Apr 8. Bioorg Chem. 2021. PMID: 33872924

7

Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV.

Hofny HA, Mohamed MFA, Gomaa HAM, Abdel-Aziz SA, Youssif BGM, El-Koussi NA, Aboraia AS. Hofny HA, et al. Among authors: gomaa ham. Bioorg Chem. 2021 Jul;112:104920. doi: 10.1016/j.bioorg.2021.104920. Epub 2021 Apr 19. Bioorg Chem. 2021. PMID: 33910078

8

Design, Synthesis, and Antibacterial Screening of Some Novel Heteroaryl-Based Ciprofloxacin Derivatives as DNA Gyrase and Topoisomerase IV Inhibitors.

Al-Wahaibi LH, Amer AA, Marzouk AA, Gomaa HAM, Youssif BGM, Abdelhamid AA. Al-Wahaibi LH, et al. Among authors: gomaa ham. Pharmaceuticals (Basel). 2021 Apr 22;14(5):399. doi: 10.3390/ph14050399. Pharmaceuticals (Basel). 2021. PMID: 33922361 Free PMC article.

9

Design, synthesis, and biological evaluation of novel EGFR inhibitors containing 5-chloro-3-hydroxymethyl-indole-2-carboxamide scaffold with apoptotic antiproliferative activity.

Mohamed FAM, Gomaa HAM, Hendawy OM, Ali AT, Farghaly HS, Gouda AM, Abdelazeem AH, Abdelrahman MH, Trembleau L, Youssif BGM. Mohamed FAM, et al. Among authors: gomaa ham. Bioorg Chem. 2021 Jul;112:104960. doi: 10.1016/j.bioorg.2021.104960. Epub 2021 May 1. Bioorg Chem. 2021. PMID: 34020242

10

Novel 1,5-diaryl pyrazole-3-carboxamides as selective COX-2/sEH inhibitors with analgesic, anti-inflammatory, and lower cardiotoxicity effects.

Hendawy OM, Gomaa HAM, Alzarea SI, Alshammari MS, Mohamed FAM, Mostafa YA, Abdelazeem AH, Abdelrahman MH, Trembleau L, Youssif BGM. Hendawy OM, et al. Among authors: gomaa ham. Bioorg Chem. 2021 Nov;116:105302. doi: 10.1016/j.bioorg.2021.105302. Epub 2021 Aug 24. Bioorg Chem. 2021. PMID: 34464816

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