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Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy.
Krishna C, DiNatale RG, Kuo F, Srivastava RM, Vuong L, Chowell D, Gupta S, Vanderbilt C, Purohit TA, Liu M, Kansler E, Nixon BG, Chen YB, Makarov V, Blum KA, Attalla K, Weng S, Salmans ML, Golkaram M, Liu L, Zhang S, Vijayaraghavan R, Pawlowski T, Reuter V, Carlo MI, Voss MH, Coleman J, Russo P, Motzer RJ, Li MO, Leslie CS, Chan TA, Hakimi AA. Krishna C, et al. Among authors: golkaram m. Cancer Cell. 2021 May 10;39(5):662-677.e6. doi: 10.1016/j.ccell.2021.03.007. Epub 2021 Apr 15. Cancer Cell. 2021. PMID: 33861994 Free PMC article.
A Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear-Cell Renal Cell Carcinoma.
Rappold PM, Vuong L, Leibold J, Chakiryan NH, Curry M, Kuo F, Sabio E, Jiang H, Nixon BG, Liu M, Berglund AE, Silagy AW, Mascareno EA, Golkaram M, Marker M, Reising A, Savchenko A, Millholland J, Chen YB, Russo P, Coleman J, Reznik E, Manley BJ, Ostrovnaya I, Makarov V, DiNatale RG, Blum KA, Ma X, Chowell D, Li MO, Solit DB, Lowe SW, Chan TA, Motzer RJ, Voss MH, Hakimi AA. Rappold PM, et al. Among authors: golkaram m. Cancer Discov. 2022 Oct 5;12(10):2308-2329. doi: 10.1158/2159-8290.CD-21-0925. Cancer Discov. 2022. PMID: 35758895 Free PMC article. Clinical Trial.
HERVs establish a distinct molecular subtype in stage II/III colorectal cancer with poor outcome.
Golkaram M, Salmans ML, Kaplan S, Vijayaraghavan R, Martins M, Khan N, Garbutt C, Wise A, Yao J, Casimiro S, Abreu C, Macedo D, Costa AL, Alvim C, Mansinho A, Filipe P, Marques da Costa P, Fernandes A, Borralho P, Ferreira C, Aldeia F, Malaquias J, Godsey J, So A, Pawlowski T, Costa L, Zhang S, Liu L. Golkaram M, et al. NPJ Genom Med. 2021 Feb 15;6(1):13. doi: 10.1038/s41525-021-00177-w. NPJ Genom Med. 2021. PMID: 33589643 Free PMC article.
Genetic and microenvironmental intra-tumor heterogeneity impacts colorectal cancer evolution and metastatic development.
Sobral D, Martins M, Kaplan S, Golkaram M, Salmans M, Khan N, Vijayaraghavan R, Casimiro S, Fernandes A, Borralho P, Ferreira C, Pinto R, Abreu C, Costa AL, Zhang S, Pawlowski T, Godsey J, Mansinho A, Macedo D, Lobo-Martins S, Filipe P, Esteves R, Coutinho J, Costa PM, Ramires A, Aldeia F, Quintela A, So A, Liu L, Grosso AR, Costa L. Sobral D, et al. Among authors: golkaram m. Commun Biol. 2022 Sep 9;5(1):937. doi: 10.1038/s42003-022-03884-x. Commun Biol. 2022. PMID: 36085309 Free PMC article.
Control over single-cell distribution of G1 lengths by WNT governs pluripotency.
Jang J, Han D, Golkaram M, Audouard M, Liu G, Bridges D, Hellander S, Chialastri A, Dey SS, Petzold LR, Kosik KS. Jang J, et al. Among authors: golkaram m. PLoS Biol. 2019 Sep 26;17(9):e3000453. doi: 10.1371/journal.pbio.3000453. eCollection 2019 Sep. PLoS Biol. 2019. PMID: 31557150 Free PMC article.
23 results