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Talquetamab, a T-Cell-Redirecting GPRC5D Bispecific Antibody for Multiple Myeloma.
N Engl J Med. 2022 Dec 15;387(24):2232-2244. doi: 10.1056/NEJMoa2204591. Epub 2022 Dec 10.
N Engl J Med. 2022.
PMID: 36507686
Clinical Trial.
A semiphysiologically based pharmacokinetic modeling approach to predict the dose-exposure relationship of an antiparasitic prodrug/active metabolite pair.
Yan GZ, Generaux CN, Yoon M, Goldsmith RB, Tidwell RR, Hall JE, Olson CA, Clewell HJ, Brouwer KL, Paine MF.
Yan GZ, et al. Among authors: goldsmith rb.
Drug Metab Dispos. 2012 Jan;40(1):6-17. doi: 10.1124/dmd.111.040063. Epub 2011 Sep 27.
Drug Metab Dispos. 2012.
PMID: 21953913
Free PMC article.
Clinical Trial.
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Application of monoclonal antibodies to measure metabolism of an anti-trypanosomal compound in vitro and in vivo.
Goldsmith RB, Gray DR, Yan Z, Generaux CN, Tidwell RR, Reisner HM.
Goldsmith RB, et al.
J Clin Lab Anal. 2010;24(3):187-94. doi: 10.1002/jcla.20380.
J Clin Lab Anal. 2010.
PMID: 20486201
Free PMC article.
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Characterization of metal binding in the active sites of acireductone dioxygenase isoforms from Klebsiella ATCC 8724.
Chai SC, Ju T, Dang M, Goldsmith RB, Maroney MJ, Pochapsky TC.
Chai SC, et al. Among authors: goldsmith rb.
Biochemistry. 2008 Feb 26;47(8):2428-38. doi: 10.1021/bi7004152. Epub 2008 Feb 1.
Biochemistry. 2008.
PMID: 18237192
Free PMC article.
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One protein, two enzymes revisited: a structural entropy switch interconverts the two isoforms of acireductone dioxygenase.
Ju T, Goldsmith RB, Chai SC, Maroney MJ, Pochapsky SS, Pochapsky TC.
Ju T, et al. Among authors: goldsmith rb.
J Mol Biol. 2006 Nov 3;363(4):823-34. doi: 10.1016/j.jmb.2006.08.060. Epub 2006 Aug 26.
J Mol Biol. 2006.
PMID: 16989860
Free PMC article.
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