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Rationale for the design of shortened derivatives of the NK-lysin-derived antimicrobial peptide NK-2 with improved activity against Gram-negative pathogens.
Andrä J, Monreal D, Martinez de Tejada G, Olak C, Brezesinski G, Gomez SS, Goldmann T, Bartels R, Brandenburg K, Moriyon I. Andrä J, et al. Among authors: goldmann t. J Biol Chem. 2007 May 18;282(20):14719-28. doi: 10.1074/jbc.M608920200. Epub 2007 Mar 27. J Biol Chem. 2007. PMID: 17389605 Free article.
Multiple peptide resistance factor (MprF)-mediated Resistance of Staphylococcus aureus against antimicrobial peptides coincides with a modulated peptide interaction with artificial membranes comprising lysyl-phosphatidylglycerol.
Andrä J, Goldmann T, Ernst CM, Peschel A, Gutsmann T. Andrä J, et al. Among authors: goldmann t. J Biol Chem. 2011 May 27;286(21):18692-700. doi: 10.1074/jbc.M111.226886. Epub 2011 Apr 7. J Biol Chem. 2011. PMID: 21474443 Free PMC article.
Structure and mode of action of the antimicrobial peptide arenicin.
Andrä J, Jakovkin I, Grötzinger J, Hecht O, Krasnosdembskaya AD, Goldmann T, Gutsmann T, Leippe M. Andrä J, et al. Among authors: goldmann t. Biochem J. 2008 Feb 15;410(1):113-22. doi: 10.1042/BJ20071051. Biochem J. 2008. PMID: 17935487
Preclinical investigations reveal the broad-spectrum neutralizing activity of peptide Pep19-2.5 on bacterial pathogenicity factors.
Heinbockel L, Sánchez-Gómez S, Martinez de Tejada G, Dömming S, Brandenburg J, Kaconis Y, Hornef M, Dupont A, Marwitz S, Goldmann T, Ernst M, Gutsmann T, Schürholz T, Brandenburg K. Heinbockel L, et al. Among authors: goldmann t. Antimicrob Agents Chemother. 2013 Mar;57(3):1480-7. doi: 10.1128/AAC.02066-12. Epub 2013 Jan 14. Antimicrob Agents Chemother. 2013. PMID: 23318793 Free PMC article.
Lipoproteins/peptides are sepsis-inducing toxins from bacteria that can be neutralized by synthetic anti-endotoxin peptides.
Martinez de Tejada G, Heinbockel L, Ferrer-Espada R, Heine H, Alexander C, Bárcena-Varela S, Goldmann T, Correa W, Wiesmüller KH, Gisch N, Sánchez-Gómez S, Fukuoka S, Schürholz T, Gutsmann T, Brandenburg K. Martinez de Tejada G, et al. Among authors: goldmann t. Sci Rep. 2015 Sep 22;5:14292. doi: 10.1038/srep14292. Sci Rep. 2015. PMID: 26390973 Free PMC article.
Therapeutical Administration of Peptide Pep19-2.5 and Ibuprofen Reduces Inflammation and Prevents Lethal Sepsis.
Heinbockel L, Marwitz S, Barcena Varela S, Ferrer-Espada R, Reiling N, Goldmann T, Gutsmann T, Mier W, Schürholz T, Drömann D, Brandenburg K, Martinez de Tejada G. Heinbockel L, et al. Among authors: goldmann t. PLoS One. 2015 Jul 21;10(7):e0133291. doi: 10.1371/journal.pone.0133291. eCollection 2015. PLoS One. 2015. PMID: 26197109 Free PMC article.
251 results