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Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes.
Goldberg AA, Richard VR, Kyryakov P, Bourque SD, Beach A, Burstein MT, Glebov A, Koupaki O, Boukh-Viner T, Gregg C, Juneau M, English AM, Thomas DY, Titorenko VI. Goldberg AA, et al. Aging (Albany NY). 2010 Jul;2(7):393-414. doi: 10.18632/aging.100168. Aging (Albany NY). 2010. PMID: 20622262 Free PMC article.
Mechanisms through which lithocholic acid delays yeast chronological aging under caloric restriction conditions.
Arlia-Ciommo A, Leonov A, Mohammad K, Beach A, Richard VR, Bourque SD, Burstein MT, Goldberg AA, Kyryakov P, Gomez-Perez A, Koupaki O, Titorenko VI. Arlia-Ciommo A, et al. Among authors: goldberg aa. Oncotarget. 2018 Oct 9;9(79):34945-34971. doi: 10.18632/oncotarget.26188. eCollection 2018 Oct 9. Oncotarget. 2018. PMID: 30405886 Free PMC article.
62 results