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Page 1
Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients.
Hassin O, Nataraj NB, Shreberk-Shaked M, Aylon Y, Yaeger R, Fontemaggi G, Mukherjee S, Maddalena M, Avioz A, Iancu O, Mallel G, Gershoni A, Grosheva I, Feldmesser E, Ben-Dor S, Golani O, Hendel A, Blandino G, Kelsen D, Yarden Y, Oren M. Hassin O, et al. Among authors: golani o. Nat Commun. 2022 May 19;13(1):2800. doi: 10.1038/s41467-022-30481-7. Nat Commun. 2022. PMID: 35589715 Free PMC article.
NKG2D ligands mediate immunosurveillance of senescent cells.
Sagiv A, Burton DG, Moshayev Z, Vadai E, Wensveen F, Ben-Dor S, Golani O, Polic B, Krizhanovsky V. Sagiv A, et al. Among authors: golani o. Aging (Albany NY). 2016 Feb;8(2):328-44. doi: 10.18632/aging.100897. Aging (Albany NY). 2016. PMID: 26878797 Free PMC article.
High-Throughput Screen Identifies Host and Microbiota Regulators of Intestinal Barrier Function.
Grosheva I, Zheng D, Levy M, Polansky O, Lichtenstein A, Golani O, Dori-Bachash M, Moresi C, Shapiro H, Del Mare-Roumani S, Valdes-Mas R, He Y, Karbi H, Chen M, Harmelin A, Straussman R, Yissachar N, Elinav E, Geiger B. Grosheva I, et al. Among authors: golani o. Gastroenterology. 2020 Nov;159(5):1807-1823. doi: 10.1053/j.gastro.2020.07.003. Epub 2020 Jul 9. Gastroenterology. 2020. PMID: 32653496
Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer.
Levi-Galibov O, Lavon H, Wassermann-Dozorets R, Pevsner-Fischer M, Mayer S, Wershof E, Stein Y, Brown LE, Zhang W, Friedman G, Nevo R, Golani O, Katz LH, Yaeger R, Laish I, Porco JA, Sahai E, Shouval DS, Kelsen D, Scherz-Shouval R. Levi-Galibov O, et al. Among authors: golani o. Nat Commun. 2020 Dec 7;11(1):6245. doi: 10.1038/s41467-020-20054-x. Nat Commun. 2020. PMID: 33288768 Free PMC article.
TP53 missense mutations in PDAC are associated with enhanced fibrosis and an immunosuppressive microenvironment.
Maddalena M, Mallel G, Nataraj NB, Shreberk-Shaked M, Hassin O, Mukherjee S, Arandkar S, Rotkopf R, Kapsack A, Lambiase G, Pellegrino B, Ben-Isaac E, Golani O, Addadi Y, Hajaj E, Eilam R, Straussman R, Yarden Y, Lotem M, Oren M. Maddalena M, et al. Among authors: golani o. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2025631118. doi: 10.1073/pnas.2025631118. Proc Natl Acad Sci U S A. 2021. PMID: 34088837 Free PMC article.
ICAM-1 on Breast Cancer Cells Suppresses Lung Metastasis but Is Dispensable for Tumor Growth and Killing by Cytotoxic T Cells.
Regev O, Kizner M, Roncato F, Dadiani M, Saini M, Castro-Giner F, Yajuk O, Kozlovski S, Levi N, Addadi Y, Golani O, Ben-Dor S, Granot Z, Aceto N, Alon R. Regev O, et al. Among authors: golani o. Front Immunol. 2022 Jul 11;13:849701. doi: 10.3389/fimmu.2022.849701. eCollection 2022. Front Immunol. 2022. PMID: 35911772 Free PMC article.
Thymic mimetic cells function beyond self-tolerance.
Givony T, Leshkowitz D, Del Castillo D, Nevo S, Kadouri N, Dassa B, Gruper Y, Khalaila R, Ben-Nun O, Gome T, Dobeš J, Ben-Dor S, Kedmi M, Keren-Shaul H, Heffner-Krausz R, Porat Z, Golani O, Addadi Y, Brenner O, Lo DD, Goldfarb Y, Abramson J. Givony T, et al. Among authors: golani o. Nature. 2023 Oct;622(7981):164-172. doi: 10.1038/s41586-023-06512-8. Epub 2023 Sep 6. Nature. 2023. PMID: 37674082
Author Correction: Thymic mimetic cells function beyond self-tolerance.
Givony T, Leshkowitz D, Del Castillo D, Nevo S, Kadouri N, Dassa B, Gruper Y, Khalaila R, Ben-Nun O, Gome T, Dobeš J, Ben-Dor S, Kedmi M, Keren-Shaul H, Heffner-Krausz R, Porat Z, Golani O, Addadi Y, Brenner O, Lo DD, Goldfarb Y, Abramson J. Givony T, et al. Among authors: golani o. Nature. 2023 Dec;624(7991):E4. doi: 10.1038/s41586-023-06881-0. Nature. 2023. PMID: 38036683 No abstract available.
The human tumor microbiome is composed of tumor type-specific intracellular bacteria.
Nejman D, Livyatan I, Fuks G, Gavert N, Zwang Y, Geller LT, Rotter-Maskowitz A, Weiser R, Mallel G, Gigi E, Meltser A, Douglas GM, Kamer I, Gopalakrishnan V, Dadosh T, Levin-Zaidman S, Avnet S, Atlan T, Cooper ZA, Arora R, Cogdill AP, Khan MAW, Ologun G, Bussi Y, Weinberger A, Lotan-Pompan M, Golani O, Perry G, Rokah M, Bahar-Shany K, Rozeman EA, Blank CU, Ronai A, Shaoul R, Amit A, Dorfman T, Kremer R, Cohen ZR, Harnof S, Siegal T, Yehuda-Shnaidman E, Gal-Yam EN, Shapira H, Baldini N, Langille MGI, Ben-Nun A, Kaufman B, Nissan A, Golan T, Dadiani M, Levanon K, Bar J, Yust-Katz S, Barshack I, Peeper DS, Raz DJ, Segal E, Wargo JA, Sandbank J, Shental N, Straussman R. Nejman D, et al. Among authors: golani o. Science. 2020 May 29;368(6494):973-980. doi: 10.1126/science.aay9189. Science. 2020. PMID: 32467386 Free PMC article.
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