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Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function.
Khani S, Topel H, Kardinal R, Tavanez AR, Josephrajan A, Larsen BDM, Gaudry MJ, Leyendecker P, Egedal NM, Güller AS, Stanic N, Ruppert PMM, Gaziano I, Hansmeier NR, Schmidt E, Klemm P, Vagliano LM, Stahl R, Duthie F, Krause JH, Bici A, Engelhard CA, Gohlke S, Frommolt P, Gnad T, Rada-Iglesias A, Pradas-Juni M, Schulz TJ, Wunderlich FT, Pfeifer A, Bartelt A, Jastroch M, Wachten D, Kornfeld JW. Khani S, et al. Among authors: gohlke s. Nat Metab. 2024 Apr 29. doi: 10.1038/s42255-024-01033-8. Online ahead of print. Nat Metab. 2024. PMID: 38684889
Adipose retinol saturase is regulated by β-adrenergic signaling and its deletion impairs lipolysis in adipocytes and acute cold tolerance in mice.
Li C, Kiefer MF, Dittrich S, Flores RE, Meng Y, Yang N, Wulff S, Gohlke S, Sommerfeld M, Wowro SJ, Petricek KM, Dürbeck D, Spranger L, Mai K, Scholz H, Schulz TJ, Schupp M. Li C, et al. Among authors: gohlke s. Mol Metab. 2024 Jan;79:101855. doi: 10.1016/j.molmet.2023.101855. Epub 2023 Dec 19. Mol Metab. 2024. PMID: 38128827 Free PMC article.
Okadaic acid activates Wnt/β-catenin-signaling in human HepaRG cells.
Dietrich J, Sommersdorf C, Gohlke S, Poetz O, Traenkle B, Rothbauer U, Hessel-Pras S, Lampen A, Braeuning A. Dietrich J, et al. Among authors: gohlke s. Arch Toxicol. 2019 Jul;93(7):1927-1939. doi: 10.1007/s00204-019-02489-4. Epub 2019 May 21. Arch Toxicol. 2019. PMID: 31115591
Identification of functional lipid metabolism biomarkers of brown adipose tissue aging.
Gohlke S, Zagoriy V, Cuadros Inostroza A, Méret M, Mancini C, Japtok L, Schumacher F, Kuhlow D, Graja A, Stephanowitz H, Jähnert M, Krause E, Wernitz A, Petzke KJ, Schürmann A, Kleuser B, Schulz TJ. Gohlke S, et al. Mol Metab. 2019 Jun;24:1-17. doi: 10.1016/j.molmet.2019.03.011. Epub 2019 Apr 4. Mol Metab. 2019. PMID: 31003944 Free PMC article.
Aging of Brown and Beige/Brite Adipose Tissue.
Graja A, Gohlke S, Schulz TJ. Graja A, et al. Among authors: gohlke s. Handb Exp Pharmacol. 2019;251:55-72. doi: 10.1007/164_2018_151. Handb Exp Pharmacol. 2019. PMID: 30141100
29 results