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Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease.
Nat Commun. 2022 Dec 5;13(1):7497. doi: 10.1038/s41467-022-35306-1.
Nat Commun. 2022.
PMID: 36470928
Free PMC article.
IL11 Activates Pancreatic Stellate Cells and Causes Pancreatic Inflammation, Fibrosis and Atrophy in a Mouse Model of Pancreatitis.
Ng B, Viswanathan S, Widjaja AA, Lim WW, Shekeran SG, Goh JWT, Tan J, Kuthubudeen F, Lim SY, Xie C, Schafer S, Adami E, Cook SA.
Ng B, et al. Among authors: goh jwt.
Int J Mol Sci. 2022 Mar 24;23(7):3549. doi: 10.3390/ijms23073549.
Int J Mol Sci. 2022.
PMID: 35408908
Free PMC article.
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IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues.
Widjaja AA, Chothani S, Viswanathan S, Goh JWT, Lim WW, Cook SA.
Widjaja AA, et al. Among authors: goh jwt.
Int J Mol Sci. 2022 Aug 10;23(16):8900. doi: 10.3390/ijms23168900.
Int J Mol Sci. 2022.
PMID: 36012165
Free PMC article.
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Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury.
Widjaja AA, Dong J, Adami E, Viswanathan S, Ng B, Pakkiri LS, Chothani SP, Singh BK, Lim WW, Zhou J, Shekeran SG, Tan J, Lim SY, Goh J, Wang M, Holgate R, Hearn A, Felkin LE, Yen PM, Dear JW, Drum CL, Schafer S, Cook SA.
Widjaja AA, et al.
Sci Transl Med. 2021 Jun 9;13(597):eaba8146. doi: 10.1126/scitranslmed.aba8146.
Sci Transl Med. 2021.
PMID: 34108253
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Hepatocyte Specific gp130 Signalling Underlies APAP Induced Liver Injury.
Dong J, Lim WW, Shekeran SG, Tan J, Lim SY, Goh JWT, George BL, Schafer S, Cook SA, Widjaja AA.
Dong J, et al. Among authors: goh jwt.
Int J Mol Sci. 2022 Jun 25;23(13):7089. doi: 10.3390/ijms23137089.
Int J Mol Sci. 2022.
PMID: 35806094
Free PMC article.
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