Goetze AM - Search Results

1

IgG2 disulfide isoform conversion kinetics.

Liu YD, Wang T, Chou R, Chen L, Kannan G, Stevenson R, Goetze AM, Jiang XG, Huang G, Dillon TM, Flynn GC. Liu YD, et al. Among authors: goetze am. Mol Immunol. 2013 Jun;54(2):217-26. doi: 10.1016/j.molimm.2012.12.005. Epub 2013 Jan 2. Mol Immunol. 2013. PMID: 23291144

2

N-terminal glutamate to pyroglutamate conversion in vivo for human IgG2 antibodies.

Liu YD, Goetze AM, Bass RB, Flynn GC. Liu YD, et al. Among authors: goetze am. J Biol Chem. 2011 Apr 1;286(13):11211-7. doi: 10.1074/jbc.M110.185041. Epub 2011 Jan 31. J Biol Chem. 2011. PMID: 21282104 Free PMC article.

3

Rapid LC-MS screening for IgG Fc modifications and allelic variants in blood.

Goetze AM, Zhang Z, Liu L, Jacobsen FW, Flynn GC. Goetze AM, et al. Mol Immunol. 2011 Oct;49(1-2):338-52. doi: 10.1016/j.molimm.2011.09.002. Epub 2011 Sep 25. Mol Immunol. 2011. PMID: 21945018

4

Assessment of naturally occurring covalent and total dimer levels in human IgG1 and IgG2.

Yang J, Goetze AM, Flynn GC. Yang J, et al. Among authors: goetze am. Mol Immunol. 2014 Mar;58(1):108-15. doi: 10.1016/j.molimm.2013.11.011. Epub 2013 Dec 8. Mol Immunol. 2014. PMID: 24321397

5

Assessing monoclonal antibody product quality attribute criticality through clinical studies.

Goetze AM, Schenauer MR, Flynn GC. Goetze AM, et al. MAbs. 2010 Sep-Oct;2(5):500-7. doi: 10.4161/mabs.2.5.12897. Epub 2010 Sep 1. MAbs. 2010. PMID: 20671426 Free PMC article. Review.

6

High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans.

Goetze AM, Liu YD, Zhang Z, Shah B, Lee E, Bondarenko PV, Flynn GC. Goetze AM, et al. Glycobiology. 2011 Jul;21(7):949-59. doi: 10.1093/glycob/cwr027. Epub 2011 Mar 18. Glycobiology. 2011. PMID: 21421994

7

Rates and impact of human antibody glycation in vivo.

Goetze AM, Liu YD, Arroll T, Chu L, Flynn GC. Goetze AM, et al. Glycobiology. 2012 Feb;22(2):221-34. doi: 10.1093/glycob/cwr141. Epub 2011 Sep 19. Glycobiology. 2012. PMID: 21930650

8

Identification and quantification of host cell protein impurities in biotherapeutics using mass spectrometry.

Schenauer MR, Flynn GC, Goetze AM. Schenauer MR, et al. Among authors: goetze am. Anal Biochem. 2012 Sep 15;428(2):150-7. doi: 10.1016/j.ab.2012.05.018. Epub 2012 May 26. Anal Biochem. 2012. PMID: 22640604

9

Profiling the effects of process changes on residual host cell proteins in biotherapeutics by mass spectrometry.

Schenauer MR, Flynn GC, Goetze AM. Schenauer MR, et al. Among authors: goetze am. Biotechnol Prog. 2013 Jul-Aug;29(4):951-7. doi: 10.1002/btpr.1748. Epub 2013 May 21. Biotechnol Prog. 2013. PMID: 23696295

10

Comprehensive tracking of host cell proteins during monoclonal antibody purifications using mass spectrometry.

Zhang Q, Goetze AM, Cui H, Wylie J, Trimble S, Hewig A, Flynn GC. Zhang Q, et al. Among authors: goetze am. MAbs. 2014 May-Jun;6(3):659-70. doi: 10.4161/mabs.28120. Epub 2014 Feb 11. MAbs. 2014. PMID: 24518299 Free PMC article.

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