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Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression.
Manta CP, Leibing T, Friedrich M, Nolte H, Adrian M, Schledzewski K, Krzistetzko J, Kirkamm C, David Schmid C, Xi Y, Stojanovic A, Tonack S, de la Torre C, Hammad S, Offermanns S, Krüger M, Cerwenka A, Platten M, Goerdt S, Géraud C. Manta CP, et al. Among authors: goerdt s. Circulation. 2022 Dec 6;146(23):1783-1799. doi: 10.1161/CIRCULATIONAHA.121.058615. Epub 2022 Nov 3. Circulation. 2022. PMID: 36325910 Free article.
Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding.
Hansen B, Longati P, Elvevold K, Nedredal GI, Schledzewski K, Olsen R, Falkowski M, Kzhyshkowska J, Carlsson F, Johansson S, Smedsrød B, Goerdt S, Johansson S, McCourt P. Hansen B, et al. Among authors: goerdt s. Exp Cell Res. 2005 Feb 1;303(1):160-73. doi: 10.1016/j.yexcr.2004.09.017. Exp Cell Res. 2005. PMID: 15572036
Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway.
Kzhyshkowska J, Mamidi S, Gratchev A, Kremmer E, Schmuttermaier C, Krusell L, Haus G, Utikal J, Schledzewski K, Scholtze J, Goerdt S. Kzhyshkowska J, et al. Among authors: goerdt s. Blood. 2006 Apr 15;107(8):3221-8. doi: 10.1182/blood-2005-07-2843. Epub 2005 Dec 15. Blood. 2006. PMID: 16357325 Free article.
341 results