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Asymmetric Synthesis and Biological Screening of Quinoxaline-Containing Synthetic Lipoxin A4 Mimetics (QNX-sLXms).
de Gaetano M, Tighe C, Gahan K, Zanetti A, Chen J, Newson J, Cacace A, Marai M, Gaffney A, Brennan E, Kantharidis P, Cooper ME, Leroy X, Perretti M, Gilroy D, Godson C, Guiry PJ. de Gaetano M, et al. Among authors: godson c. J Med Chem. 2021 Jul 8;64(13):9193-9216. doi: 10.1021/acs.jmedchem.1c00403. Epub 2021 Jun 17. J Med Chem. 2021. PMID: 34138563 Free PMC article.
The Lipoxin A4 receptor is coupled to SHP-2 activation: implications for regulation of receptor tyrosine kinases.
Mitchell D, O'Meara SJ, Gaffney A, Crean JK, Kinsella BT, Godson C. Mitchell D, et al. Among authors: godson c. J Biol Chem. 2007 May 25;282(21):15606-18. doi: 10.1074/jbc.M611004200. Epub 2007 Apr 2. J Biol Chem. 2007. PMID: 17403678 Free article.
., Mitchell, D., Shattock, R., Martin, F., Brady, H. R., and Godson, C. (2002) FASEB J. 16, 1817-1819). Here we demonstrate that the lipoxin A(4) (LXA(4)) receptor is coupled to activation and recruitment of the SHP-2 (SH2 domain-containing tyrosine phosphatase-2) w …
., Mitchell, D., Shattock, R., Martin, F., Brady, H. R., and Godson, C. (2002) FASEB J. 16, 1817-1819). Here we demonstrate th …
165 results