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Page 1
TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.
Mariani CJ, Vasanthakumar A, Madzo J, Yesilkanal A, Bhagat T, Yu Y, Bhattacharyya S, Wenger RH, Cohn SL, Nanduri J, Verma A, Prabhakar NR, Godley LA. Mariani CJ, et al. Among authors: godley la. Cell Rep. 2014 Jun 12;7(5):1343-1352. doi: 10.1016/j.celrep.2014.04.040. Epub 2014 May 15. Cell Rep. 2014. PMID: 24835990 Free PMC article.
DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.
Shah MY, Vasanthakumar A, Barnes NY, Figueroa ME, Kamp A, Hendrick C, Ostler KR, Davis EM, Lin S, Anastasi J, Le Beau MM, Moskowitz IP, Melnick A, Pytel P, Godley LA. Shah MY, et al. Among authors: godley la. Cancer Res. 2010 Jul 15;70(14):5840-50. doi: 10.1158/0008-5472.CAN-10-0847. Epub 2010 Jun 29. Cancer Res. 2010. PMID: 20587527 Free PMC article.
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.
Figueroa ME, Abdel-Wahab O, Lu C, Ward PS, Patel J, Shih A, Li Y, Bhagwat N, Vasanthakumar A, Fernandez HF, Tallman MS, Sun Z, Wolniak K, Peeters JK, Liu W, Choe SE, Fantin VR, Paietta E, Löwenberg B, Licht JD, Godley LA, Delwel R, Valk PJ, Thompson CB, Levine RL, Melnick A. Figueroa ME, et al. Among authors: godley la. Cancer Cell. 2010 Dec 14;18(6):553-67. doi: 10.1016/j.ccr.2010.11.015. Epub 2010 Dec 9. Cancer Cell. 2010. PMID: 21130701 Free PMC article.
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
Moran-Crusio K, Reavie L, Shih A, Abdel-Wahab O, Ndiaye-Lobry D, Lobry C, Figueroa ME, Vasanthakumar A, Patel J, Zhao X, Perna F, Pandey S, Madzo J, Song C, Dai Q, He C, Ibrahim S, Beran M, Zavadil J, Nimer SD, Melnick A, Godley LA, Aifantis I, Levine RL. Moran-Crusio K, et al. Among authors: godley la. Cancer Cell. 2011 Jul 12;20(1):11-24. doi: 10.1016/j.ccr.2011.06.001. Epub 2011 Jun 30. Cancer Cell. 2011. PMID: 21723200 Free PMC article.
Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors.
Pronier E, Almire C, Mokrani H, Vasanthakumar A, Simon A, da Costa Reis Monte Mor B, Massé A, Le Couédic JP, Pendino F, Carbonne B, Larghero J, Ravanat JL, Casadevall N, Bernard OA, Droin N, Solary E, Godley LA, Vainchenker W, Plo I, Delhommeau F. Pronier E, et al. Among authors: godley la. Blood. 2011 Sep 1;118(9):2551-5. doi: 10.1182/blood-2010-12-324707. Epub 2011 Jul 6. Blood. 2011. PMID: 21734233 Free PMC article.
DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation.
Shaknovich R, Cerchietti L, Tsikitas L, Kormaksson M, De S, Figueroa ME, Ballon G, Yang SN, Weinhold N, Reimers M, Clozel T, Luttrop K, Ekstrom TJ, Frank J, Vasanthakumar A, Godley LA, Michor F, Elemento O, Melnick A. Shaknovich R, et al. Among authors: godley la. Blood. 2011 Sep 29;118(13):3559-69. doi: 10.1182/blood-2011-06-357996. Epub 2011 Aug 9. Blood. 2011. PMID: 21828137 Free PMC article.
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
Szulwach KE, Li X, Li Y, Song CX, Wu H, Dai Q, Irier H, Upadhyay AK, Gearing M, Levey AI, Vasanthakumar A, Godley LA, Chang Q, Cheng X, He C, Jin P. Szulwach KE, et al. Among authors: godley la. Nat Neurosci. 2011 Oct 30;14(12):1607-16. doi: 10.1038/nn.2959. Nat Neurosci. 2011. PMID: 22037496 Free PMC article.
Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis.
Nanduri J, Makarenko V, Reddy VD, Yuan G, Pawar A, Wang N, Khan SA, Zhang X, Kinsman B, Peng YJ, Kumar GK, Fox AP, Godley LA, Semenza GL, Prabhakar NR. Nanduri J, et al. Among authors: godley la. Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2515-20. doi: 10.1073/pnas.1120600109. Epub 2012 Jan 9. Proc Natl Acad Sci U S A. 2012. PMID: 22232674 Free PMC article.
224 results