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VDJdb in 2019: database extension, new analysis infrastructure and a T-cell receptor motif compendium.
Bagaev DV, Vroomans RMA, Samir J, Stervbo U, Rius C, Dolton G, Greenshields-Watson A, Attaf M, Egorov ES, Zvyagin IV, Babel N, Cole DK, Godkin AJ, Sewell AK, Kesmir C, Chudakov DM, Luciani F, Shugay M. Bagaev DV, et al. Among authors: godkin aj. Nucleic Acids Res. 2020 Jan 8;48(D1):D1057-D1062. doi: 10.1093/nar/gkz874. Nucleic Acids Res. 2020. PMID: 31588507 Free PMC article.
Potent T cell agonism mediated by a very rapid TCR/pMHC interaction.
Boulter JM, Schmitz N, Sewell AK, Godkin AJ, Bachmann MF, Gallimore AM. Boulter JM, et al. Among authors: godkin aj. Eur J Immunol. 2007 Mar;37(3):798-806. doi: 10.1002/eji.200636743. Eur J Immunol. 2007. PMID: 17295390 Free PMC article.
Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers.
Lissina A, Ladell K, Skowera A, Clement M, Edwards E, Seggewiss R, van den Berg HA, Gostick E, Gallagher K, Jones E, Melenhorst JJ, Godkin AJ, Peakman M, Price DA, Sewell AK, Wooldridge L. Lissina A, et al. Among authors: godkin aj. J Immunol Methods. 2009 Jan 1;340(1):11-24. doi: 10.1016/j.jim.2008.09.014. Epub 2008 Oct 16. J Immunol Methods. 2009. PMID: 18929568 Free PMC article.
Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining.
Clement M, Ladell K, Ekeruche-Makinde J, Miles JJ, Edwards ES, Dolton G, Williams T, Schauenburg AJ, Cole DK, Lauder SN, Gallimore AM, Godkin AJ, Burrows SR, Price DA, Sewell AK, Wooldridge L. Clement M, et al. Among authors: godkin aj. J Immunol. 2011 Jul 15;187(2):654-63. doi: 10.4049/jimmunol.1003941. Epub 2011 Jun 15. J Immunol. 2011. PMID: 21677135 Free PMC article.
T-cell receptor (TCR)-peptide specificity overrides affinity-enhancing TCR-major histocompatibility complex interactions.
Cole DK, Miles KM, Madura F, Holland CJ, Schauenburg AJ, Godkin AJ, Bulek AM, Fuller A, Akpovwa HJ, Pymm PG, Liddy N, Sami M, Li Y, Rizkallah PJ, Jakobsen BK, Sewell AK. Cole DK, et al. Among authors: godkin aj. J Biol Chem. 2014 Jan 10;289(2):628-38. doi: 10.1074/jbc.M113.522110. Epub 2013 Nov 6. J Biol Chem. 2014. PMID: 24196962 Free PMC article.
Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells.
Dolton G, Lissina A, Skowera A, Ladell K, Tungatt K, Jones E, Kronenberg-Versteeg D, Akpovwa H, Pentier JM, Holland CJ, Godkin AJ, Cole DK, Neller MA, Miles JJ, Price DA, Peakman M, Sewell AK. Dolton G, et al. Among authors: godkin aj. Clin Exp Immunol. 2014 Jul;177(1):47-63. doi: 10.1111/cei.12339. Clin Exp Immunol. 2014. PMID: 24673376 Free PMC article.
Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs.
Tungatt K, Bianchi V, Crowther MD, Powell WE, Schauenburg AJ, Trimby A, Donia M, Miles JJ, Holland CJ, Cole DK, Godkin AJ, Peakman M, Straten PT, Svane IM, Sewell AK, Dolton G. Tungatt K, et al. Among authors: godkin aj. J Immunol. 2015 Jan 1;194(1):463-74. doi: 10.4049/jimmunol.1401785. Epub 2014 Dec 1. J Immunol. 2015. PMID: 25452566 Free PMC article.
108 results