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DNA damage-induced interaction between a lineage addiction oncogenic transcription factor and the MRN complex shapes a tissue-specific DNA Damage Response and cancer predisposition.
Binet R, Lambert JP, Tomkova M, Tischfield S, Baggiolini A, Picaud S, Sarkar S, Louphrasitthiphol P, Dias D, Carreira S, Humphrey T, Fillipakopoulos P, White R, Goding CR. Binet R, et al. Among authors: goding cr. bioRxiv [Preprint]. 2023 Apr 21:2023.04.21.537819. doi: 10.1101/2023.04.21.537819. bioRxiv. 2023. PMID: 37131595 Free PMC article. Preprint.
DNA damage remodels the MITF interactome to increase melanoma genomic instability.
Binet R, Lambert JP, Tomkova M, Tischfield S, Baggiolini A, Picaud S, Sarkar S, Louphrasitthiphol P, Dias D, Carreira S, Humphrey TC, Fillipakopoulos P, White R, Goding CR. Binet R, et al. Among authors: goding cr. Genes Dev. 2024 Feb 13;38(1-2):70-94. doi: 10.1101/gad.350740.123. Genes Dev. 2024. PMID: 38316520 Free PMC article.
An adverse tumor-protective effect of IDO1 inhibition.
Kenski JCN, Huang X, Vredevoogd DW, de Bruijn B, Traets JJH, Ibáñez-Molero S, Schieven SM, van Vliet A, Krijgsman O, Kuilman T, Pozniak J, Loayza-Puch F, Terry AM, Müller J, Logtenberg MEW, de Bruijn M, Levy P, Körner PR, Goding CR, Schumacher TN, Marine JC, Agami R, Peeper DS. Kenski JCN, et al. Among authors: goding cr. Cell Rep Med. 2023 Feb 21;4(2):100941. doi: 10.1016/j.xcrm.2023.100941. Cell Rep Med. 2023. PMID: 36812891 Free PMC article.
The lipid droplet protein DHRS3 is a regulator of melanoma cell state.
Johns E, Ma Y, Louphrasitthipol P, Peralta C, Hunter MV, Raymond JH, Molina H, Goding CR, White RM. Johns E, et al. Among authors: goding cr. bioRxiv [Preprint]. 2024 Mar 28:2024.03.25.586589. doi: 10.1101/2024.03.25.586589. bioRxiv. 2024. PMID: 38586016 Free PMC article. Preprint.
Mi-2β promotes immune evasion in melanoma by activating EZH2 methylation.
Li C, Wang Z, Yao L, Lin X, Jian Y, Li Y, Zhang J, Shao J, Tran PD, Hagman JR, Cao M, Cong Y, Li HY, Goding CR, Xu ZX, Liao X, Miao X, Cui R. Li C, et al. Among authors: goding cr. Nat Commun. 2024 Mar 9;15(1):2163. doi: 10.1038/s41467-024-46422-5. Nat Commun. 2024. PMID: 38461299 Free PMC article.
Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation.
Chocarro-Calvo A, Jociles-Ortega M, García-Martinez JM, Louphrasitthiphol P, Garcia YV, Ramírez-Sánchez A, Chauhan J, Fiuza MC, Duran M, García-Jiménez C, Goding CR. Chocarro-Calvo A, et al. Among authors: goding cr. bioRxiv [Preprint]. 2024 Jan 24:2024.01.21.576568. doi: 10.1101/2024.01.21.576568. bioRxiv. 2024. PMID: 38328032 Free PMC article. Preprint.
163 results