Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2007 1
2008 1
2012 2
2013 3
2014 1
2015 4
2016 5
2017 7
2018 10
2019 5
2020 6
2021 8
2022 8
2023 6
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

58 results

Results by year

Filters applied: . Clear all
Page 1
Showing results for goiania yl
Search for Godhania YL instead (1 results)
3-Benzoyl-1-[4-(methyl-sulfan-yl)phen-yl]thio-urea.
Castro Rde P, Macedo FC Jr, Brito TO, de Fátima A, Sabino JR. Castro Rde P, et al. Acta Crystallogr Sect E Struct Rep Online. 2013 May 18;69(Pt 6):o923. doi: 10.1107/S1600536813013159. Print 2013 Jun 1. Acta Crystallogr Sect E Struct Rep Online. 2013. PMID: 23795092 Free PMC article.
An intra-molecular N-HO hydrogen bond leads to a six-membered pseudo-ring [r.m.s. deviation = 0.0212 A, maximum deviation = 0.033 (1) A for the N atom bearing the benzoyl group] in the central unit. The benzene and (methyl-sulfan-yl)benzene ring [r.m.s = 0.0028 A and large …
An intra-molecular N-HO hydrogen bond leads to a six-membered pseudo-ring [r.m.s. deviation = 0.0212 A, maximum deviation = 0.033 (1) A for …
rac-5-(1-Methyl-eth-yl)-2-sulfanylidene-imidazolidin-4-one.
Castro Rde P, Macedo FC Jr, Brito TO, de Fátima A, Sabino JR. Castro Rde P, et al. Acta Crystallogr Sect E Struct Rep Online. 2013 Apr 5;69(Pt 5):o643. doi: 10.1107/S1600536813008337. Print 2013 May 1. Acta Crystallogr Sect E Struct Rep Online. 2013. PMID: 23723808 Free PMC article.
Novel choline analog 2-(4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)ethan-1-ol produces sympathoinhibition, hypotension, and antihypertensive effects.
Menegatti R, Carvalho FS, Lião LM, Villavicencio B, Verli H, Mourão AA, Xavier CH, Castro CH, Pedrino GR, Franco OL, Oliveira-Silva I, Ashpole NM, Silva ON, Costa EA, Fajemiroye JO. Menegatti R, et al. Naunyn Schmiedebergs Arch Pharmacol. 2019 Sep;392(9):1071-1083. doi: 10.1007/s00210-019-01649-8. Epub 2019 May 2. Naunyn Schmiedebergs Arch Pharmacol. 2019. PMID: 31049606
The current study investigates the effects of 2-(4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)ethan-1-ol (LQFM032) on cardiovascular function and cholinergic-nitric oxide signaling. ...
The current study investigates the effects of 2-(4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)ethan-1-ol (LQFM032) on ca …
Neuropharmacological Activity of the New Piperazine Derivative 2-(4-((1- Phenyl-1H-Pyrazol-4-yl)Methyl)Piperazin-1-yl)Ethyl Acetate is Modulated by Serotonergic and GABAergic Pathways.
Almeida LS, Santana IGC, da Silva Moreira LK, Turones LC, Sanz G, Vaz BG, de Carvalho FS, Lião LM, Menegatti R, Costa EA, de Brito AF. Almeida LS, et al. CNS Neurol Disord Drug Targets. 2022;21(6):520-532. doi: 10.2174/1871527320666211112173233. CNS Neurol Disord Drug Targets. 2022. PMID: 34781873
OBJECTIVES: In this study, we proposed the design, synthesis of a new compound, 2-(4-((1- phenyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)ethyl acetate (LQFM192), pharmacological evaluation of its anxiolytic-like and antidepressant-like activities, as well as the possi …
OBJECTIVES: In this study, we proposed the design, synthesis of a new compound, 2-(4-((1- phenyl-1H-pyrazol-4-yl)methyl)piperazin-1- …
Anxiolytic-like effect of 2-(4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)ethan-1-ol is mediated through the benzodiazepine and nicotinic pathways.
Brito AF, Fajemiroye JO, Neri HFS, Silva DM, Silva DPB, Sanz G, Vaz BG, de Carvalho FS, Ghedini PC, Lião LM, Menegatti R, Costa EA. Brito AF, et al. Chem Biol Drug Des. 2017 Sep;90(3):432-442. doi: 10.1111/cbdd.12961. Epub 2017 Mar 6. Chem Biol Drug Des. 2017. PMID: 28160425
In this study, we proposed the design, synthesis of a new compound 2-(4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)ethan-1-ol (LQFM032), and pharmacological evaluation of its anxiolytic-like effect. ...
In this study, we proposed the design, synthesis of a new compound 2-(4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)ethan …
Anti-inflammatory, antinociceptive, and vasorelaxant effects of a new pyrazole compound 5-(1-(2-fluorophenyl)-1H-pyrazol-4-yl)-1H-tetrazole: role of NO/cGMP pathway and calcium channels.
de Oliveira LP, Florentino IF, Silva DPB, Pazini F, de Carvalho FS, Sanz G, Vaz BG, da Rocha FF, Fajemiroye JO, Ghedini PC, Lião LM, Menegatti R, Costa EA, de Oliveira TS. de Oliveira LP, et al. Can J Physiol Pharmacol. 2023 May 1;101(5):216-225. doi: 10.1139/cjpp-2022-0428. Epub 2023 Mar 3. Can J Physiol Pharmacol. 2023. PMID: 36866837
In this sense, this study presents a new pyrazole derivative 5-(1-(2-fluorophenyl)-1H-pyrazol-4-yl)-1H-tetrazole (LQFM039) and evaluated the anti-inflammatory, analgesic, and vasorelaxant effects of this compound as well the mechanisms of action involved in the pharmacolog …
In this sense, this study presents a new pyrazole derivative 5-(1-(2-fluorophenyl)-1H-pyrazol-4-yl)-1H-tetrazole (LQFM039) and evalua …
A new piperazine derivative: 1-(4-(3,5-di-tert-butyl-4-hydroxybenzyl) piperazin-1-yl)-2-methoxyethan-1-one with antioxidant and central activity.
Brito AF, Braga PCCS, Moreira LKS, Silva DM, Silva DPB, Sanz G, Vaz BG, de Carvalho FS, Lião LM, Silva RR, Noël F, Neri HFS, Ghedini PC, de Carvalho MF, de S Gil E, Costa EA, Menegatti R. Brito AF, et al. Naunyn Schmiedebergs Arch Pharmacol. 2018 Mar;391(3):255-269. doi: 10.1007/s00210-017-1451-7. Epub 2017 Dec 19. Naunyn Schmiedebergs Arch Pharmacol. 2018. PMID: 29260264
In the scope of a research program aimed at developing new drugs for the treatment of central nervous system diseases, we describe herein the synthesis and pharmacological evaluation of 1-(4-(3,5-di-tert-butyl-4-hydroxybenzyl) piperazin-1-yl)-2-methoxyethan-1-one (LQFM180) …
In the scope of a research program aimed at developing new drugs for the treatment of central nervous system diseases, we describe herein th …
KIO4 -mediated Selective Hydroxymethylation/Methylenation of Imidazo-Heteroarenes: A Greener Approach.
Franco MS, Saba S, Rafique J, Braga AL. Franco MS, et al. Angew Chem Int Ed Engl. 2021 Aug 16;60(34):18454-18460. doi: 10.1002/anie.202104503. Epub 2021 Jul 16. Angew Chem Int Ed Engl. 2021. PMID: 34097781
., Zolpidem. Furthermore, by using glycerol, bis(imidazo[1,2-a]pyridin-3-yl)methane derivatives were selectively obtained in good to excellent yields....
., Zolpidem. Furthermore, by using glycerol, bis(imidazo[1,2-a]pyridin-3-yl)methane derivatives were selectively obtained in good to …
New pyrazole derivative 5-[1-(4-fluorophenyl)-1H-pyrazol-4-yl]-2H-tetrazole: synthesis and assessment of some biological activities.
de Oliveira LP, da Silva DP, Florentino IF, Fajemiroye JO, de Oliveira TS, Marcelino RI, Pazini F, Lião LM, Ghedini PC, de Moura SS, Valadares MC, de Carvalho VV, Vaz BG, Menegatti R, Costa EA. de Oliveira LP, et al. Chem Biol Drug Des. 2017 Jan;89(1):124-135. doi: 10.1111/cbdd.12838. Epub 2016 Sep 14. Chem Biol Drug Des. 2017. PMID: 27526659
In response to pyrazole compounds' antipyretic, analgesic, and anti-inflammatory effects, this study sought to evaluate the analgesic, anti-inflammatory, and vasorelaxant effects, as well as the mechanisms of action, of a new pyrazole derivative, 5-[1-(4-fluorophenyl)-1H-pyrazol- …
In response to pyrazole compounds' antipyretic, analgesic, and anti-inflammatory effects, this study sought to evaluate the analgesic, anti- …
58 results