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Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia.
Membrez M, Migliavacca E, Christen S, Yaku K, Trieu J, Lee AK, Morandini F, Giner MP, Stiner J, Makarov MV, Garratt ES, Vasiloglou MF, Chanvillard L, Dalbram E, Ehrlich AM, Sanchez-Garcia JL, Canto C, Karagounis LG, Treebak JT, Migaud ME, Heshmat R, Razi F, Karnani N, Ostovar A, Farzadfar F, Tay SKH, Sanders MJ, Lillycrop KA, Godfrey KM, Nakagawa T, Moco S, Koopman R, Lynch GS, Sorrentino V, Feige JN. Membrez M, et al. Among authors: godfrey km. Nat Metab. 2024 Mar;6(3):433-447. doi: 10.1038/s42255-024-00997-x. Epub 2024 Mar 19. Nat Metab. 2024. PMID: 38504132 Free PMC article.
Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylation and changes in histone modifications.
Lillycrop KA, Slater-Jefferies JL, Hanson MA, Godfrey KM, Jackson AA, Burdge GC. Lillycrop KA, et al. Among authors: godfrey km. Br J Nutr. 2007 Jun;97(6):1064-73. doi: 10.1017/S000711450769196X. Epub 2007 Apr 12. Br J Nutr. 2007. PMID: 17433129 Free PMC article.
Epigenetic gene promoter methylation at birth is associated with child's later adiposity.
Godfrey KM, Sheppard A, Gluckman PD, Lillycrop KA, Burdge GC, McLean C, Rodford J, Slater-Jefferies JL, Garratt E, Crozier SR, Emerald BS, Gale CR, Inskip HM, Cooper C, Hanson MA. Godfrey KM, et al. Diabetes. 2011 May;60(5):1528-34. doi: 10.2337/db10-0979. Epub 2011 Apr 6. Diabetes. 2011. PMID: 21471513 Free PMC article.
Evaluation of methylation status of the eNOS promoter at birth in relation to childhood bone mineral content.
Harvey NC, Lillycrop KA, Garratt E, Sheppard A, McLean C, Burdge G, Slater-Jefferies J, Rodford J, Crozier S, Inskip H, Emerald BS, Gale CR, Hanson M, Gluckman P, Godfrey K, Cooper C. Harvey NC, et al. Calcif Tissue Int. 2012 Feb;90(2):120-7. doi: 10.1007/s00223-011-9554-5. Epub 2011 Dec 8. Calcif Tissue Int. 2012. PMID: 22159788 Free PMC article.
614 results