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CryoEM reconstructions of membrane proteins solved in several amphipathic solvents, nanodisc, amphipol and detergents, yield amphipathic belts of similar sizes corresponding to a common ordered solvent layer.
Zampieri V, Gobet A, Robert X, Falson P, Chaptal V. Zampieri V, et al. Among authors: gobet a. Biochim Biophys Acta Biomembr. 2021 Nov 1;1863(11):183693. doi: 10.1016/j.bbamem.2021.183693. Epub 2021 Jul 13. Biochim Biophys Acta Biomembr. 2021. PMID: 34271006 Free article.
Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter.
Chaptal V, Zampieri V, Wiseman B, Orelle C, Martin J, Nguyen KA, Gobet A, Di Cesare M, Magnard S, Javed W, Eid J, Kilburg A, Peuchmaur M, Marcoux J, Monticelli L, Hogbom M, Schoehn G, Jault JM, Boumendjel A, Falson P. Chaptal V, et al. Among authors: gobet a. Sci Adv. 2022 Jan 28;8(4):eabg9215. doi: 10.1126/sciadv.abg9215. Epub 2022 Jan 26. Sci Adv. 2022. PMID: 35080979 Free PMC article.
Conformational space exploration of cryo-EM structures by variability refinement.
Afonine PV, Gobet A, Moissonnier L, Martin J, Poon BK, Chaptal V. Afonine PV, et al. Among authors: gobet a. Biochim Biophys Acta Biomembr. 2023 Apr;1865(4):184133. doi: 10.1016/j.bbamem.2023.184133. Epub 2023 Feb 3. Biochim Biophys Acta Biomembr. 2023. PMID: 36738875 Free article. Review.
The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains.
Di Cesare M, Kaplan E, Rendon J, Gerbaud G, Valimehr S, Gobet A, Ngo TT, Chaptal V, Falson P, Martinho M, Dorlet P, Hanssen E, Jault JM, Orelle C. Di Cesare M, et al. Among authors: gobet a. J Biol Chem. 2024 Jan;300(1):105546. doi: 10.1016/j.jbc.2023.105546. Epub 2023 Dec 9. J Biol Chem. 2024. PMID: 38072053 Free PMC article.
37 results