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Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease.
Ghodsian N, Abner E, Emdin CA, Gobeil É, Taba N, Haas ME, Perrot N, Manikpurage HD, Gagnon É, Bourgault J, St-Amand A, Couture C, Mitchell PL, Bossé Y, Mathieu P, Vohl MC, Tchernof A, Thériault S, Khera AV, Esko T, Arsenault BJ. Ghodsian N, et al. Among authors: gobeil e. Cell Rep Med. 2021 Nov 3;2(11):100437. doi: 10.1016/j.xcrm.2021.100437. eCollection 2021 Nov 16. Cell Rep Med. 2021. PMID: 34841290 Free PMC article.
Mendelian Randomization Analysis Identifies Blood Tyrosine Levels as a Biomarker of Non-Alcoholic Fatty Liver Disease.
Gobeil É, Maltais-Payette I, Taba N, Brière F, Ghodsian N, Abner E, Bourgault J, Gagnon E, Manikpurage HD, Couture C, Mitchell PL, Mathieu P, Julien F, Corbeil J, Vohl MC, Thériault S, Esko T, Tchernof A, Arsenault BJ. Gobeil É, et al. Metabolites. 2022 May 13;12(5):440. doi: 10.3390/metabo12050440. Metabolites. 2022. PMID: 35629944 Free PMC article.
Mendelian randomization prioritizes abdominal adiposity as an independent causal factor for liver fat accumulation and cardiometabolic diseases.
Gagnon E, Pelletier W, Gobeil É, Bourgault J, Manikpurage HD, Maltais-Payette I, Abner E, Taba N, Esko T, Mitchell PL, Ghodsian N, Després JP, Vohl MC, Tchernof A, Thériault S, Arsenault BJ. Gagnon E, et al. Among authors: gobeil e. Commun Med (Lond). 2022 Oct 13;2:130. doi: 10.1038/s43856-022-00196-3. eCollection 2022. Commun Med (Lond). 2022. PMID: 36249462 Free PMC article.
Impact of loss-of-function in angiopoietin-like 4 on the human phenome.
Gagnon E, Bourgault J, Gobeil É, Thériault S, Arsenault BJ. Gagnon E, et al. Among authors: gobeil e. Atherosclerosis. 2024 Apr 18;393:117558. doi: 10.1016/j.atherosclerosis.2024.117558. Online ahead of print. Atherosclerosis. 2024. PMID: 38703417 Free article.
Genetic inhibition of angiopoietin-like protein-3, lipids, and cardiometabolic risk.
Gobeil É, Bourgault J, Mitchell PL, Houessou U, Gagnon E, Girard A, Paulin A, Manikpurage HD, Côté V, Couture C, Marceau S, Bossé Y, Thériault S, Mathieu P, Vohl MC, Tchernof A, Arsenault BJ. Gobeil É, et al. Eur Heart J. 2024 Mar 1;45(9):707-721. doi: 10.1093/eurheartj/ehad845. Eur Heart J. 2024. PMID: 38243829
Large-scale metabolomic profiling and incident non-alcoholic fatty liver disease.
Gagnon E, Manikpurage HD, Mitchell PL, Girard A, Gobeil É, Bourgault J, Bégin F, Marette A, Thériault S, Arsenault BJ. Gagnon E, et al. Among authors: gobeil e. iScience. 2023 Jun 14;26(7):107127. doi: 10.1016/j.isci.2023.107127. eCollection 2023 Jul 21. iScience. 2023. PMID: 37456853 Free PMC article.
Genetic control of body weight by the human brain proteome.
Gagnon E, Girard A, Gobeil É, Bourgault J, Couture C, Mitchell PL, Bouchard C, Tremblay A, Mathieu P, Michaud A, Pérusse L, Arsenault BJ. Gagnon E, et al. Among authors: gobeil e. iScience. 2023 Mar 11;26(4):106376. doi: 10.1016/j.isci.2023.106376. eCollection 2023 Apr 21. iScience. 2023. PMID: 37013190 Free PMC article.
Proteome-Wide Mendelian Randomization Identifies Causal Links Between Blood Proteins and Acute Pancreatitis.
Bourgault J, Abner E, Manikpurage HD, Pujol-Gualdo N, Laisk T; Estonian Biobank Research Team; Gobeil É, Gagnon E, Girard A, Mitchell PL, Thériault S, Esko T, Mathieu P, Arsenault BJ. Bourgault J, et al. Among authors: gobeil e. Gastroenterology. 2023 May;164(6):953-965.e3. doi: 10.1053/j.gastro.2023.01.028. Epub 2023 Feb 1. Gastroenterology. 2023. PMID: 36736436