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Page 1
Automatic local resolution-based sharpening of cryo-EM maps.
Ramírez-Aportela E, Vilas JL, Glukhova A, Melero R, Conesa P, Martínez M, Maluenda D, Mota J, Jiménez A, Vargas J, Marabini R, Sexton PM, Carazo JM, Sorzano COS. Ramírez-Aportela E, et al. Among authors: glukhova a. Bioinformatics. 2020 Feb 1;36(3):765-772. doi: 10.1093/bioinformatics/btz671. Bioinformatics. 2020. PMID: 31504163 Free PMC article.
Novel Irreversible Agonists Acting at the A1 Adenosine Receptor.
Jörg M, Glukhova A, Abdul-Ridha A, Vecchio EA, Nguyen AT, Sexton PM, White PJ, May LT, Christopoulos A, Scammells PJ. Jörg M, et al. Among authors: glukhova a. J Med Chem. 2016 Dec 22;59(24):11182-11194. doi: 10.1021/acs.jmedchem.6b01561. Epub 2016 Dec 13. J Med Chem. 2016. PMID: 27958734
Phase-plate cryo-EM structure of a class B GPCR-G-protein complex.
Liang YL, Khoshouei M, Radjainia M, Zhang Y, Glukhova A, Tarrasch J, Thal DM, Furness SGB, Christopoulos G, Coudrat T, Danev R, Baumeister W, Miller LJ, Christopoulos A, Kobilka BK, Wootten D, Skiniotis G, Sexton PM. Liang YL, et al. Among authors: glukhova a. Nature. 2017 Jun 1;546(7656):118-123. doi: 10.1038/nature22327. Epub 2017 Apr 24. Nature. 2017. PMID: 28437792 Free PMC article.
Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex.
Liang YL, Khoshouei M, Glukhova A, Furness SGB, Zhao P, Clydesdale L, Koole C, Truong TT, Thal DM, Lei S, Radjainia M, Danev R, Baumeister W, Wang MW, Miller LJ, Christopoulos A, Sexton PM, Wootten D. Liang YL, et al. Among authors: glukhova a. Nature. 2018 Mar 1;555(7694):121-125. doi: 10.1038/nature25773. Epub 2018 Feb 21. Nature. 2018. PMID: 29466332
Structure of the adenosine-bound human adenosine A1 receptor-Gi complex.
Draper-Joyce CJ, Khoshouei M, Thal DM, Liang YL, Nguyen ATN, Furness SGB, Venugopal H, Baltos JA, Plitzko JM, Danev R, Baumeister W, May LT, Wootten D, Sexton PM, Glukhova A, Christopoulos A. Draper-Joyce CJ, et al. Among authors: glukhova a. Nature. 2018 Jun;558(7711):559-563. doi: 10.1038/s41586-018-0236-6. Epub 2018 Jun 20. Nature. 2018. PMID: 29925945
Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor.
Liang YL, Khoshouei M, Deganutti G, Glukhova A, Koole C, Peat TS, Radjainia M, Plitzko JM, Baumeister W, Miller LJ, Hay DL, Christopoulos A, Reynolds CA, Wootten D, Sexton PM. Liang YL, et al. Among authors: glukhova a. Nature. 2018 Sep;561(7724):492-497. doi: 10.1038/s41586-018-0535-y. Epub 2018 Sep 12. Nature. 2018. PMID: 30209400 Free PMC article.
Dominant Negative G Proteins Enhance Formation and Purification of Agonist-GPCR-G Protein Complexes for Structure Determination.
Liang YL, Zhao P, Draper-Joyce C, Baltos JA, Glukhova A, Truong TT, May LT, Christopoulos A, Wootten D, Sexton PM, Furness SGB. Liang YL, et al. Among authors: glukhova a. ACS Pharmacol Transl Sci. 2018 Jul 26;1(1):12-20. doi: 10.1021/acsptsci.8b00017. eCollection 2018 Sep 14. ACS Pharmacol Transl Sci. 2018. PMID: 32219201 Free PMC article.
51 results