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Elongator and the role of its subcomplexes in human diseases.
Gaik M, Kojic M, Wainwright BJ, Glatt S. Gaik M, et al. Among authors: glatt s. EMBO Mol Med. 2023 Feb 8;15(2):e16418. doi: 10.15252/emmm.202216418. Epub 2022 Nov 30. EMBO Mol Med. 2023. PMID: 36448458 Free PMC article. Review.
Architecture of the yeast Elongator complex.
Dauden MI, Kosinski J, Kolaj-Robin O, Desfosses A, Ori A, Faux C, Hoffmann NA, Onuma OF, Breunig KD, Beck M, Sachse C, Séraphin B, Glatt S, Müller CW. Dauden MI, et al. Among authors: glatt s. EMBO Rep. 2017 Feb;18(2):264-279. doi: 10.15252/embr.201643353. Epub 2016 Dec 14. EMBO Rep. 2017. PMID: 27974378 Free PMC article.
Elongator mutation in mice induces neurodegeneration and ataxia-like behavior.
Kojic M, Gaik M, Kiska B, Salerno-Kochan A, Hunt S, Tedoldi A, Mureev S, Jones A, Whittle B, Genovesi LA, Adolphe C, Brown DL, Stow JL, Alexandrov K, Sah P, Glatt S, Wainwright BJ. Kojic M, et al. Among authors: glatt s. Nat Commun. 2018 Aug 10;9(1):3195. doi: 10.1038/s41467-018-05765-6. Nat Commun. 2018. PMID: 30097576 Free PMC article.
How Elongator Acetylates tRNA Bases.
Abbassi NE, Biela A, Glatt S, Lin TY. Abbassi NE, et al. Among authors: glatt s. Int J Mol Sci. 2020 Nov 3;21(21):8209. doi: 10.3390/ijms21218209. Int J Mol Sci. 2020. PMID: 33152999 Free PMC article. Review.
Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype.
Kojic M, Gawda T, Gaik M, Begg A, Salerno-Kochan A, Kurniawan ND, Jones A, Drożdżyk K, Kościelniak A, Chramiec-Głąbik A, Hediyeh-Zadeh S, Kasherman M, Shim WJ, Sinniah E, Genovesi LA, Abrahamsen RK, Fenger CD, Madsen CG, Cohen JS, Fatemi A, Stark Z, Lunke S, Lee J, Hansen JK, Boxill MF, Keren B, Marey I, Saenz MS, Brown K, Alexander SA, Mureev S, Batzilla A, Davis MJ, Piper M, Bodén M, Burne THJ, Palpant NJ, Møller RS, Glatt S, Wainwright BJ. Kojic M, et al. Among authors: glatt s. Nat Commun. 2021 May 11;12(1):2678. doi: 10.1038/s41467-021-22888-5. Nat Commun. 2021. PMID: 33976153 Free PMC article.
Molecular insights into RNA recognition and gene regulation by the TRIM-NHL protein Mei-P26.
Salerno-Kochan A, Horn A, Ghosh P, Nithin C, Kościelniak A, Meindl A, Strauss D, Krutyhołowa R, Rossbach O, Bujnicki JM, Gaik M, Medenbach J, Glatt S. Salerno-Kochan A, et al. Among authors: glatt s. Life Sci Alliance. 2022 May 5;5(8):e202201418. doi: 10.26508/lsa.202201418. Print 2022 Aug. Life Sci Alliance. 2022. PMID: 35512835 Free PMC article.
Functional divergence of the two Elongator subcomplexes during neurodevelopment.
Gaik M, Kojic M, Stegeman MR, Öncü-Öner T, Kościelniak A, Jones A, Mohamed A, Chau PYS, Sharmin S, Chramiec-Głąbik A, Indyka P, Rawski M, Biela A, Dobosz D, Millar A, Chau V, Ünalp A, Piper M, Bellingham MC, Eichler EE, Nickerson DA, Güleryüz H, Abbassi NEH, Jazgar K, Davis MJ, Mercimek-Andrews S, Cingöz S, Wainwright BJ, Glatt S. Gaik M, et al. Among authors: glatt s. EMBO Mol Med. 2022 Jul 7;14(7):e15608. doi: 10.15252/emmm.202115608. Epub 2022 Jun 13. EMBO Mol Med. 2022. PMID: 35698786 Free PMC article.
Cryo-EM structure of the fully assembled Elongator complex.
Jaciuk M, Scherf D, Kaszuba K, Gaik M, Rau A, Kościelniak A, Krutyhołowa R, Rawski M, Indyka P, Graziadei A, Chramiec-Głąbik A, Biela A, Dobosz D, Lin TY, Abbassi NE, Hammermeister A, Rappsilber J, Kosinski J, Schaffrath R, Glatt S. Jaciuk M, et al. Among authors: glatt s. Nucleic Acids Res. 2023 Mar 21;51(5):2011-2032. doi: 10.1093/nar/gkac1232. Nucleic Acids Res. 2023. PMID: 36617428 Free PMC article.
Modulation of translational decoding by m6A modification of mRNA.
Jain S, Koziej L, Poulis P, Kaczmarczyk I, Gaik M, Rawski M, Ranjan N, Glatt S, Rodnina MV. Jain S, et al. Among authors: glatt s. Nat Commun. 2023 Aug 8;14(1):4784. doi: 10.1038/s41467-023-40422-7. Nat Commun. 2023. PMID: 37553384 Free PMC article.
291 results