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LXR modulation blocks prostaglandin E2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model.
Li N, Rivéra-Bermúdez MA, Zhang M, Tejada J, Glasson SS, Collins-Racie LA, Lavallie ER, Wang Y, Chang KC, Nagpal S, Morris EA, Flannery CR, Yang Z. Li N, et al. Among authors: glasson ss. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3734-9. doi: 10.1073/pnas.0911377107. Epub 2010 Feb 3. Proc Natl Acad Sci U S A. 2010. PMID: 20133709 Free PMC article.
Elevated aggrecanase activity in a rat model of joint injury is attenuated by an aggrecanase specific inhibitor.
Chockalingam PS, Sun W, Rivera-Bermudez MA, Zeng W, Dufield DR, Larsson S, Lohmander LS, Flannery CR, Glasson SS, Georgiadis KE, Morris EA. Chockalingam PS, et al. Among authors: glasson ss. Osteoarthritis Cartilage. 2011 Mar;19(3):315-23. doi: 10.1016/j.joca.2010.12.004. Epub 2010 Dec 14. Osteoarthritis Cartilage. 2011. PMID: 21163358 Free article.
Osteoarthritis severity is sex dependent in a surgical mouse model.
Ma HL, Blanchet TJ, Peluso D, Hopkins B, Morris EA, Glasson SS. Ma HL, et al. Among authors: glasson ss. Osteoarthritis Cartilage. 2007 Jun;15(6):695-700. doi: 10.1016/j.joca.2006.11.005. Epub 2007 Jan 3. Osteoarthritis Cartilage. 2007. PMID: 17207643 Free article.
27 results