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OMICmAge: An integrative multi-omics approach to quantify biological age with electronic medical records.
Chen Q, Dwaraka VB, Carreras-Gallo N, Mendez K, Chen Y, Begum S, Kachroo P, Prince N, Went H, Mendez T, Lin A, Turner L, Moqri M, Chu SH, Kelly RS, Weiss ST, Rattray NJW, Gladyshev VN, Karlson E, Wheelock C, Mathé EA, Dahlin A, McGeachie MJ, Smith R, Lasky-Su JA. Chen Q, et al. Among authors: gladyshev vn. bioRxiv [Preprint]. 2023 Oct 24:2023.10.16.562114. doi: 10.1101/2023.10.16.562114. bioRxiv. 2023. PMID: 37904959 Free PMC article. Preprint.
Biomarkers of aging for the identification and evaluation of longevity interventions.
Moqri M, Herzog C, Poganik JR; Biomarkers of Aging Consortium; Justice J, Belsky DW, Higgins-Chen A, Moskalev A, Fuellen G, Cohen AA, Bautmans I, Widschwendter M, Ding J, Fleming A, Mannick J, Han JJ, Zhavoronkov A, Barzilai N, Kaeberlein M, Cummings S, Kennedy BK, Ferrucci L, Horvath S, Verdin E, Maier AB, Snyder MP, Sebastiano V, Gladyshev VN. Moqri M, et al. Among authors: gladyshev vn. Cell. 2023 Aug 31;186(18):3758-3775. doi: 10.1016/j.cell.2023.08.003. Cell. 2023. PMID: 37657418 Free PMC article. Review.
Biological age is increased by stress and restored upon recovery.
Poganik JR, Zhang B, Baht GS, Tyshkovskiy A, Deik A, Kerepesi C, Yim SH, Lu AT, Haghani A, Gong T, Hedman AM, Andolf E, Pershagen G, Almqvist C, Clish CB, Horvath S, White JP, Gladyshev VN. Poganik JR, et al. Among authors: gladyshev vn. Cell Metab. 2023 May 2;35(5):807-820.e5. doi: 10.1016/j.cmet.2023.03.015. Epub 2023 Apr 21. Cell Metab. 2023. PMID: 37086720 Free PMC article.
Epigenetic clocks, aging, and cancer.
Johnstone SE, Gladyshev VN, Aryee MJ, Bernstein BE. Johnstone SE, et al. Among authors: gladyshev vn. Science. 2022 Dec 23;378(6626):1276-1277. doi: 10.1126/science.abn4009. Epub 2022 Dec 22. Science. 2022. PMID: 36548410
A torpor-like state (TLS) in mice slows blood epigenetic aging and prolongs healthspan.
Jayne L, Lavin-Peter A, Roessler J, Tyshkovskiy A, Antoszewski M, Ren E, Markovski A, Sun S, Yao H, Sankaran VG, Gladyshev VN, Brooke RT, Horvath S, Griffith EC, Hrvatin S. Jayne L, et al. Among authors: gladyshev vn. bioRxiv [Preprint]. 2024 Mar 25:2024.03.20.585828. doi: 10.1101/2024.03.20.585828. bioRxiv. 2024. PMID: 38585858 Free PMC article. Preprint.
Molecular Damage in Aging.
Gladyshev VN, Kritchevsky SB, Clarke SG, Cuervo AM, Fiehn O, de Magalhães JP, Mau T, Maes M, Moritz R, Niedernhofer LJ, Van Schaftingen E, Tranah GJ, Walsh K, Yura Y, Zhang B, Cummings SR. Gladyshev VN, et al. Nat Aging. 2021 Dec;1(12):1096-1106. doi: 10.1038/s43587-021-00150-3. Epub 2021 Dec 20. Nat Aging. 2021. PMID: 36846190 Free PMC article. Review.
Chemically induced reprogramming to reverse cellular aging.
Yang JH, Petty CA, Dixon-McDougall T, Lopez MV, Tyshkovskiy A, Maybury-Lewis S, Tian X, Ibrahim N, Chen Z, Griffin PT, Arnold M, Li J, Martinez OA, Behn A, Rogers-Hammond R, Angeli S, Gladyshev VN, Sinclair DA. Yang JH, et al. Among authors: gladyshev vn. Aging (Albany NY). 2023 Jul 12;15(13):5966-5989. doi: 10.18632/aging.204896. Epub 2023 Jul 12. Aging (Albany NY). 2023. PMID: 37437248 Free PMC article.
The beginning of becoming a human.
Loseva PA, Gladyshev VN. Loseva PA, et al. Among authors: gladyshev vn. Aging (Albany NY). 2024 May 6;16. doi: 10.18632/aging.205824. Online ahead of print. Aging (Albany NY). 2024. PMID: 38713165 Free article.
450 results