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TRPM8 inhibits endothelial cell migration via a non-channel function by trapping the small GTPase Rap1.
Genova T, Grolez GP, Camillo C, Bernardini M, Bokhobza A, Richard E, Scianna M, Lemonnier L, Valdembri D, Munaron L, Philips MR, Mattot V, Serini G, Prevarskaya N, Gkika D, Pla AF. Genova T, et al. Among authors: gkika d. J Cell Biol. 2017 Jul 3;216(7):2107-2130. doi: 10.1083/jcb.201506024. Epub 2017 May 26. J Cell Biol. 2017. PMID: 28550110 Free PMC article.
4TM-TRPM8 channels are new gatekeepers of the ER-mitochondria Ca2+ transfer.
Bidaux G, Gordienko D, Shapovalov G, Farfariello V, Borowiec AS, Iamshanova O, Lemonnier L, Gueguinou M, Guibon R, Fromont G, Paillard M, Gouriou Y, Chouabe C, Dewailly E, Gkika D, López-Alvarado P, Carlos Menéndez J, Héliot L, Slomianny C, Prevarskaya N. Bidaux G, et al. Among authors: gkika d. Biochim Biophys Acta Mol Cell Res. 2018 Jul;1865(7):981-994. doi: 10.1016/j.bbamcr.2018.04.007. Epub 2018 Apr 18. Biochim Biophys Acta Mol Cell Res. 2018. PMID: 29678654 Free article.
TRPM8 and prostate: a cold case?
Noyer L, Grolez GP, Prevarskaya N, Gkika D, Lemonnier L. Noyer L, et al. Among authors: gkika d. Pflugers Arch. 2018 Oct;470(10):1419-1429. doi: 10.1007/s00424-018-2169-1. Epub 2018 Jun 20. Pflugers Arch. 2018. PMID: 29926226 Review.
TRPV1 variants impair intracellular Ca2+ signaling and may confer susceptibility to malignant hyperthermia.
Vanden Abeele F, Lotteau S, Ducreux S, Dubois C, Monnier N, Hanna A, Gkika D, Romestaing C, Noyer L, Flourakis M, Tessier N, Al-Mawla R, Chouabe C, Lefai E, Lunardi J, Hamilton S, Fauré J, Van Coppenolle F, Prevarskaya N. Vanden Abeele F, et al. Among authors: gkika d. Genet Med. 2019 Feb;21(2):441-450. doi: 10.1038/s41436-018-0066-9. Epub 2018 Jun 21. Genet Med. 2019. PMID: 29930394 Free PMC article.
Ca2+ Channel Toolkit in Neuroendocrine Tumors.
Fiorio Pla A, Gkika D. Fiorio Pla A, et al. Among authors: gkika d. Neuroendocrinology. 2020;110(1-2):147-154. doi: 10.1159/000501397. Epub 2019 Jun 10. Neuroendocrinology. 2020. PMID: 31177261 Free article. Review.
TRPC3 shapes the ER-mitochondria Ca2+ transfer characterizing tumour-promoting senescence.
Farfariello V, Gordienko DV, Mesilmany L, Touil Y, Germain E, Fliniaux I, Desruelles E, Gkika D, Roudbaraki M, Shapovalov G, Noyer L, Lebas M, Allart L, Zienthal-Gelus N, Iamshanova O, Bonardi F, Figeac M, Laine W, Kluza J, Marchetti P, Quesnel B, Metzger D, Bernard D, Parys JB, Lemonnier L, Prevarskaya N. Farfariello V, et al. Among authors: gkika d. Nat Commun. 2022 Feb 17;13(1):956. doi: 10.1038/s41467-022-28597-x. Nat Commun. 2022. PMID: 35177596 Free PMC article.
TRPM8 as an Anti-Tumoral Target in Prostate Cancer Growth and Metastasis Dissemination.
Grolez GP, Chinigò G, Barras A, Hammadi M, Noyer L, Kondratska K, Bulk E, Oullier T, Marionneau-Lambot S, Le Mée M, Rétif S, Lerondel S, Bongiovanni A, Genova T, Roger S, Boukherroub R, Schwab A, Fiorio Pla A, Gkika D. Grolez GP, et al. Among authors: gkika d. Int J Mol Sci. 2022 Jun 15;23(12):6672. doi: 10.3390/ijms23126672. Int J Mol Sci. 2022. PMID: 35743115 Free PMC article.
62 results