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Patient-derived micro-organospheres enable clinical precision oncology.
Ding S, Hsu C, Wang Z, Natesh NR, Millen R, Negrete M, Giroux N, Rivera GO, Dohlman A, Bose S, Rotstein T, Spiller K, Yeung A, Sun Z, Jiang C, Xi R, Wilkin B, Randon PM, Williamson I, Nelson DA, Delubac D, Oh S, Rupprecht G, Isaacs J, Jia J, Chen C, Shen JP, Kopetz S, McCall S, Smith A, Gjorevski N, Walz AC, Antonia S, Marrer-Berger E, Clevers H, Hsu D, Shen X. Ding S, et al. Among authors: gjorevski n. Cell Stem Cell. 2022 Jun 2;29(6):905-917.e6. doi: 10.1016/j.stem.2022.04.006. Epub 2022 May 3. Cell Stem Cell. 2022. PMID: 35508177 Free PMC article.
Drug discovery through stem cell-based organoid models.
Ranga A, Gjorevski N, Lutolf MP. Ranga A, et al. Among authors: gjorevski n. Adv Drug Deliv Rev. 2014 Apr;69-70:19-28. doi: 10.1016/j.addr.2014.02.006. Epub 2014 Feb 26. Adv Drug Deliv Rev. 2014. PMID: 24582599 Review.
Biomaterials approaches in stem cell mechanobiology.
Gjorevski N, Lutolf M. Gjorevski N, et al. Prog Mol Biol Transl Sci. 2014;126:257-78. doi: 10.1016/B978-0-12-394624-9.00011-7. Prog Mol Biol Transl Sci. 2014. PMID: 25081622 Review.
Analysis of off-tumour toxicities of T-cell-engaging bispecific antibodies via donor-matched intestinal organoids and tumouroids.
Harter MF, Recaldin T, Gerard R, Avignon B, Bollen Y, Esposito C, Guja-Jarosz K, Kromer K, Filip A, Aubert J, Schneider A, Bacac M, Bscheider M, Stokar-Regenscheit N, Piscuoglio S, Beumer J, Gjorevski N. Harter MF, et al. Among authors: gjorevski n. Nat Biomed Eng. 2024 Apr;8(4):345-360. doi: 10.1038/s41551-023-01156-5. Epub 2023 Dec 19. Nat Biomed Eng. 2024. PMID: 38114742 Free PMC article.
Tissue geometry drives deterministic organoid patterning.
Gjorevski N, Nikolaev M, Brown TE, Mitrofanova O, Brandenberg N, DelRio FW, Yavitt FM, Liberali P, Anseth KS, Lutolf MP. Gjorevski N, et al. Science. 2022 Jan 7;375(6576):eaaw9021. doi: 10.1126/science.aaw9021. Epub 2022 Jan 7. Science. 2022. PMID: 34990240 Free PMC article.
Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies.
Kerns SJ, Belgur C, Petropolis D, Kanellias M, Barrile R, Sam J, Weinzierl T, Fauti T, Freimoser-Grundschober A, Eckmann J, Hage C, Geiger M, Ng PR, Tien-Street W, Manatakis DV, Micallef V, Gerard R, Bscheider M, Breous-Nystrom E, Schneider A, Giusti AM, Bertinetti-Lapatki C, Grant HS, Roth AB, Hamilton GA, Singer T, Karalis K, Moisan A, Bruenker P, Klein C, Bacac M, Gjorevski N, Cabon L. Kerns SJ, et al. Among authors: gjorevski n. Elife. 2021 Aug 11;10:e67106. doi: 10.7554/eLife.67106. Elife. 2021. PMID: 34378534 Free PMC article.
31 results